ID   A0A2T7ETC5_9POAL        Unreviewed;       479 AA.
AC   A0A2T7ETC5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE   AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN   ORFNames=GQ55_2G286600 {ECO:0000313|EMBL:PUZ71085.1};
OS   Panicum hallii var. hallii.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum;
OC   Panicum sect. Panicum.
OX   NCBI_TaxID=1504633 {ECO:0000313|EMBL:PUZ71085.1, ECO:0000313|Proteomes:UP000244336};
RN   [1] {ECO:0000313|EMBL:PUZ71085.1, ECO:0000313|Proteomes:UP000244336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HAL2 {ECO:0000313|Proteomes:UP000244336};
RA   Lovell J., Jenkins J., Lowry D., Mamidi S., Sreedasyam A., Weng X.,
RA   Barry K., Bonette J., Campitelli B., Daum C., Gordon S., Gould B.,
RA   Lipzen A., MacQueen A., Palacio-Mejia J., Plott C., Shakirov E., Shu S.,
RA   Yoshinaga Y., Zane M., Rokhsar D., Grimwood J., Schmutz J., Juenger T.;
RT   "WGS assembly of Panicum hallii var. hallii HAL2.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC       2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC       ECO:0000256|RuleBase:RU004914}.
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DR   EMBL; CM009750; PUZ71085.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7ETC5; -.
DR   STRING; 1504633.A0A2T7ETC5; -.
DR   EnsemblPlants; PUZ71085; PUZ71085; GQ55_2G286600.
DR   Gramene; PUZ71085; PUZ71085; GQ55_2G286600.
DR   Proteomes; UP000244336; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   CDD; cd13132; MATE_eukaryotic; 1.
DR   InterPro; IPR045069; MATE_euk.
DR   InterPro; IPR002528; MATE_fam.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR   PANTHER; PTHR11206:SF342; PROTEIN DETOXIFICATION; 1.
DR   Pfam; PF01554; MatE; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|RuleBase:RU004914};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244336};
KW   Transmembrane {ECO:0000256|RuleBase:RU004914};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT   TRANSMEM        36..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        69..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        118..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        155..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        210..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        333..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        377..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        406..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
FT   TRANSMEM        436..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004914"
SQ   SEQUENCE   479 AA;  51519 MW;  425BF59793FBAD73 CRC64;
     MESQSDVPLI SELPEQRGGG RIPGLAKDVW VESKKLWVVA GPAAFTRLTF YGMTVVSQAF
     AGHIGDLELA AFSVAATVIS GLSFGFFVGM ASAMETLCGQ AYGARQYHMM GIYLQRSWLV
     LLGVAVLLTP TYIFSGPLLA ALGQPADLSR QAGSVALYLL PLHFVYAIIL PLNKFLQCQR
     KNWVAAVTTA AVFPVHVAAT WLLVRHFRLG VFGAATALTV SWGLATAGLL SYAFGGGCPE
     TWRGFSASAF VDLKDFVKLS AASGVMLCLE NWYYRILVFL TGYVKNAELA VDALSICISY
     AGWEMMIHLG FLAGTGVRVA NELGAANGLG AKFATIVSMT TSFLISLFIS SLVLIFHDKL
     AMVFSSSEAV IRAVDSISIL LALTILLNGI QPVLSGVAVG SGWQALVAYV NIGSYYLIGV
     PFGFLLGWGF HHGVQGIWVG MIVGTMVQTL ILACIVIQCD WNDEALKASS RMRRWSRHK
//