ID   A0A2T7EWK2_9POAL        Unreviewed;       628 AA.
AC   A0A2T7EWK2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN   ORFNames=GQ55_2G374400 {ECO:0000313|EMBL:PUZ72199.1};
OS   Panicum hallii var. hallii.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum;
OC   Panicum sect. Panicum.
OX   NCBI_TaxID=1504633 {ECO:0000313|EMBL:PUZ72199.1, ECO:0000313|Proteomes:UP000244336};
RN   [1] {ECO:0000313|EMBL:PUZ72199.1, ECO:0000313|Proteomes:UP000244336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HAL2 {ECO:0000313|Proteomes:UP000244336};
RA   Lovell J., Jenkins J., Lowry D., Mamidi S., Sreedasyam A., Weng X.,
RA   Barry K., Bonette J., Campitelli B., Daum C., Gordon S., Gould B.,
RA   Lipzen A., MacQueen A., Palacio-Mejia J., Plott C., Shakirov E., Shu S.,
RA   Yoshinaga Y., Zane M., Rokhsar D., Grimwood J., Schmutz J., Juenger T.;
RT   "WGS assembly of Panicum hallii var. hallii HAL2.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC       known as the alpha DNA polymerase-primase complex) which plays an
CC       essential role in the initiation of DNA synthesis.
CC       {ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC       {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
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DR   EMBL; CM009750; PUZ72199.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7EWK2; -.
DR   STRING; 1504633.A0A2T7EWK2; -.
DR   EnsemblPlants; PUZ72199; PUZ72199; GQ55_2G374400.
DR   Gramene; PUZ72199; PUZ72199; GQ55_2G374400.
DR   Proteomes; UP000244336; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.60; -; 2.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016722; DNA_pol_alpha_bsu.
DR   InterPro; IPR013627; Pol_alpha_B_N.
DR   PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR   PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   Pfam; PF08418; Pol_alpha_B_N; 1.
DR   PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244336}.
FT   DOMAIN          26..238
FT                   /note="DNA polymerase alpha subunit B N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08418"
FT   DOMAIN          367..578
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
FT   REGION          114..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  69311 MW;  3CA4C5976575B3E6 CRC64;
     MEAEIRAEFE SSGFSIGGAG PEDAAQILST LLTYCINYKM SPGDLVSNWE VYYLNRQLDG
     LKLERSYVDG FLSHLQNEVK ERLIEEEANL HVYSSNDVDM LFNNSHADEA AFLDTPGSKQ
     EKPPGESSNT ELTPLTSDRP SSSRMAKTNG DRITPFATRV NKFTQQYVLN SDNAAIMPSK
     HEAETTEDEL IRRIQPSQRC SLQVQRSQPE PGCRFMYDRM EDRFNYLEDR IRKSATLFSA
     SGLCGEPADA TLASEEKMFA VGMVTCDGEG RLNEKSILLQ GSVEHSRGER VRLDLKDLDH
     FSLFPGQVVG IEGHNPSGHC FVASKLIDLL PVSVDAQLPS AKKQAVDDGS HHQNSDAGTL
     SRALSSVIAA GPYTTTDNLL FEPLQELLSY ACRKQPQLLI LMGPFIDSDH PDIKKGTVDQ
     SFHDIFYSEV LRKIQDFTQY LGNTVRVILI PSVCDAHHDF VFPQPAFDLN LPEDITHQIS
     SLANPSLFSS NQIHFGCCTV DILKQISGLE ISRKPPAGKP GDRIGRLATH ILKQQSYYPL
     YPPAGGVPLD FSLANEALEI SSTPDVLLLP SDLAPFAKVL SLGEGSDDQK PFICLNPGRL
     AKGIGGGTFV DLYYNEDTSR TNASIIRI
//