ID A0A2T7NBE4_POMCA Unreviewed; 400 AA.
AC A0A2T7NBE4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=choline-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00026101};
DE EC=2.7.7.15 {ECO:0000256|ARBA:ARBA00026101};
GN ORFNames=C0Q70_21037 {ECO:0000313|EMBL:PVD18488.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD18488.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD18488.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD18488.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD18488.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylcholine biosynthesis;
CC phosphatidylcholine from phosphocholine: step 1/2.
CC {ECO:0000256|ARBA:ARBA00025706}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD18488.1}.
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DR EMBL; PZQS01000014; PVD18488.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7NBE4; -.
DR STRING; 400727.A0A2T7NBE4; -.
DR EnsemblMetazoa; XM_025223325.1; XP_025079110.1; LOC112555113.
DR UniPathway; UPA00753; UER00739.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg14.
DR GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; IEA:InterPro.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR045049; Pcy1-like.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR10739:SF13; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR10739; CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119}.
FT DOMAIN 115..243
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 347..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 45760 MW; B0EC41083CC3A409 CRC64;
MLLRPPGCSQ LVTSVKGGAT DFQVERLTHH HNTQTQMAMS ADVEKGMEKV AVGRKRAHNG
RQISKLSLQP EINVGPAPYH YESLAVQNRE ACDYSIRISF EDAKKGLVSR PVRVYADGIY
DMFHAGHARQ LMQAKMAFPN TYLIVGVCSD ELTNKKKGRT VMNEFERYEG VRHCRYVDEV
VVDAPWTLDL DFLTLHKIDF VAHDDLPYTT GSADDVYKFV KERGMFLPTE RTEGISTTDV
ITRIIKDYDV YVRRNLARGY SHKDLNVSYM KAKRIKIKEN YTKLEEKLKD KGKEFIASWK
ESMDRGNLLL HRWEEKSKEF IGNFVDMFGK DGKLNKWFTE NTMRIGRALS PSRSPPRSSS
PSPTDFEDID VSPPAKRGRY SPGLSADDFT DDEDYQDDGK
//
