ID   A0A2T7NEW5_POMCA        Unreviewed;       272 AA.
AC   A0A2T7NEW5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   03-MAY-2023, entry version 15.
DE   RecName: Full=GPN-loop GTPase 2 {ECO:0000256|ARBA:ARBA00014588, ECO:0000256|RuleBase:RU365059};
GN   ORFNames=C0Q70_20214 {ECO:0000313|EMBL:PVD19723.1};
OS   Pomacea canaliculata (Golden apple snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX   NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD19723.1, ECO:0000313|Proteomes:UP000245119};
RN   [1] {ECO:0000313|EMBL:PVD19723.1, ECO:0000313|Proteomes:UP000245119}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD19723.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PVD19723.1};
RA   Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA   Zhang G., Qian W., Fan W.;
RT   "The genome of golden apple snail Pomacea canaliculata provides insight
RT   into stress tolerance and invasive adaptation.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Small GTPase required for proper localization of RNA
CC       polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC       step prior to nuclear import. {ECO:0000256|ARBA:ARBA00003181,
CC       ECO:0000256|RuleBase:RU365059}.
CC   -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC       {ECO:0000256|RuleBase:RU365059}.
CC   -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC       {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVD19723.1}.
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DR   EMBL; PZQS01000013; PVD19723.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7NEW5; -.
DR   STRING; 400727.A0A2T7NEW5; -.
DR   EnsemblMetazoa; XM_025221848.1; XP_025077633.1; LOC112554197.
DR   OrthoDB; 168004at2759; -.
DR   Proteomes; UP000245119; Miscellaneous, Linkage group lg13.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd17871; GPN2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004130; Gpn.
DR   InterPro; IPR030231; Gpn2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR21231:SF3; GPN-LOOP GTPASE 2; 1.
DR   PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR   Pfam; PF03029; ATP_bind_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|RuleBase:RU365059};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU365059};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245119}.
SQ   SEQUENCE   272 AA;  31047 MW;  C07A3707722359BB CRC64;
     MAQFLEGLGR QVSVINLDPA NDNVPYRCDV DISELITVND VMEHLKLGPN GGFVYCMEYL
     EKNMDWLLKR LTPLKDKYLL FDLPGQVELY THNNAARNIV KQLVDTEDYR LVAIHLVDSH
     YCSDPGKFIA VLLTSLTTML QMALPHINVL SKADLIEKHG RLDFNLDFYT EVLDLSYLLG
     HLQDDPLLSK YKRLNEVIVG VVEDYSLVNF IPLNVQDKET MLQVRKAADK ASGYVFGEGE
     DRTLEGLMSC AVGAEFEYEK IKNVREKYMD TE
//