ID A0A2T7NG85_POMCA Unreviewed; 437 AA.
AC A0A2T7NG85;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=WH1 domain-containing protein {ECO:0000259|PROSITE:PS50229};
GN ORFNames=C0Q70_20659 {ECO:0000313|EMBL:PVD20165.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD20165.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD20165.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD20165.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD20165.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- SIMILARITY: Belongs to the Homer family.
CC {ECO:0000256|ARBA:ARBA00023606}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD20165.1}.
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DR EMBL; PZQS01000013; PVD20165.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7NG85; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg13.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.
DR GO; GO:0035256; F:G protein-coupled glutamate receptor binding; IEA:InterPro.
DR GO; GO:0007216; P:G protein-coupled glutamate receptor signaling pathway; IEA:InterPro.
DR CDD; cd01206; EVH1_Homer_Vesl; 1.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045027; Homer.
DR InterPro; IPR044100; Homer_EVH1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR10918; HOMER; 1.
DR PANTHER; PTHR10918:SF5; HOMER, ISOFORM E; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50229; WH1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 56..168
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT REGION 173..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 242..391
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 181..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 49365 MW; FF010A3C4123BA48 CRC64;
MWSEGERLNT PLVIRRASSW RELGANTSSF GVPVDPNWTT NSYGTEYGNT TASGQFRQIG
QQPIFSTKAH VFQIDPETKK NWIPASKVAV SVSYYYDSTR NTYRIISVDG SKAIINSTIT
PNMTFTKTSQ KFGQWSDARA NTVYGLGFNT EAELAKFIEK FKEVKELTRR AVATEKPSSE
VNGGIDGSPQ PTPTRTSLHQ RTNSLSSIQT DSTNLQQRRN SFTQGSNGLP SNHSEAQLKY
ENDRLKLALA QSSANAKKWE VELTTLKNNN ARLTAALQES TANVEEWKKQ LATYKEENAR
LRKKVLEKEH EGNVQDSDSQ ALQQEMQALG EEATRLKGDN KLHQQEIVRL TKQLEEMTSR
EALTSSFQAR IQNLEEENHN LILKLQDVQR QLQESRSSRD TDSQELLQLQ EALGSKITDL
YELHEQIIAS IRKESNS
//
