ID A0A2T7NVZ7_POMCA Unreviewed; 890 AA.
AC A0A2T7NVZ7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=C0Q70_15824 {ECO:0000313|EMBL:PVD25324.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD25324.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD25324.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD25324.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD25324.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD25324.1}.
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DR EMBL; PZQS01000009; PVD25324.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7NVZ7; -.
DR STRING; 400727.A0A2T7NVZ7; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg9.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024862; TRPV.
DR PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 186..218
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 245..277
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 437..653
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 96..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 101020 MW; AC2778F6CD8105CA CRC64;
MSHESLALGK EACEFLRPVA TKVVRHCREA EEMYPLLSDQ GPDRVKEIAK TKMMTYLYNC
GKGAVIEKSE YIKWCNNRKA KFKAFQEESE LPGKSEKSEW ELKHKLESKP EEKTEEELLR
EFQEDPINKF EPHEACWDLN KRGGVGETPF HLCYLMDSPV HFEVGKALLE VFPKLACDVY
EGEEYFGESA LHIAVMLDDL DIVQLLVQNG ANVNQRATGR FFLPEDLKKN PDPTAATNYD
GYAYYGEYPL AFAACRGNQD IYDYLIDHGA NPNFQDSFGN TVLHMVVIHC QPGMFRYAVQ
HNIAPAQTDI LNKQNLTPLT LASKLGRSDI FRDMLDLGSV EFWRFSHVTC SAYPLAAIDS
IGPNGEHNWH SALMIIVDGE SDEHLEMLEG GVVWQLLKEK WKTFAKRRFL ERLAIACVHL
VLFSVAIYIR PSGPSLLDYT GAVDAVRYFC EVIVCLSCTA TIAMEIIEIS SRGFWSFLKN
CSHAPAHTVN LVSCLLILAC IPFRFLQLYE VEDILLIIAA PCSWFFLLFF ARGVQLTGPF
VTMIYKMLRG DLIRFGIIYL IFLIGFTQGF YFLFRDVTDD DDKGAKKFET FPETILTLFQ
MTLGEFKYDA FGLSRHVLLT KLVFVIFMIL MPILLLNMLI AMMGNTYTQV ISKSEKQWRK
QWAKIVVVLE RGFSKKQLLQ FQKDYSVNAR ETTQKLGKEV IRQLRTHKRD KNDTFQLHKR
FGTAVSDDAG IPNLSSTVDQ LAWEQDIDLS KGQTFVADAD QLGSISPRYA KRQDPSQTST
SVSSKVFSVP SHITGSGERH NQRHSQQAAS SAASPPPGSV HRLRFPYNRV APLSHLPPVE
NTFLTLNVDN LDSSQEDNKS TKSMFISLEP LTNHDTYSMG KSVGEDEKSE
//
