ID A0A2T7P375_POMCA Unreviewed; 764 AA.
AC A0A2T7P375;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Dystrophin {ECO:0008006|Google:ProtNLM};
GN ORFNames=C0Q70_10444 {ECO:0000313|EMBL:PVD27869.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD27869.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD27869.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD27869.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD27869.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD27869.1}.
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DR EMBL; PZQS01000006; PVD27869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7P375; -.
DR STRING; 400727.A0A2T7P375; -.
DR EnsemblMetazoa; XM_025243519.1; XP_025099304.1; LOC112567040.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg6.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd14686; bZIP; 1.
DR CDD; cd16242; EFh_DMD_like; 1.
DR CDD; cd00176; SPEC; 1.
DR CDD; cd00201; WW; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF14; DYSTROPHIN-1; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00435; Spectrin; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00150; SPEC; 1.
DR SMART; SM00456; WW; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 120..153
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 377..433
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 573..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1..28
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 618..652
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 573..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 85706 MW; B011B19875545177 CRC64;
MTLFHEAMED LEQHLTEAER EKGAWQGVGD ILIKELPAEI EATKNFQQKY APLQGEIDSV
NDQANDLQSA DVILSHVNVR RLEDFNTRWK ALQISIEDRL KQLQDALRAF GPHSQHFLAA
SVASPWERAV AGNKVPYFIN HVTEKTQWDH PVFAVLFDEL SALNDIRFAA YRTGMKLRML
QKKLGLHLVD MTVASEAFER HGLRGQNDKL IEVTEMIECL SSMYEQIAAQ RSTSSVPVDV
PLCVDLVLNW ILNVYDTVRS GKVRVLSFKV GVILLCSGQL EDKYRFMFRL IADTNGFADQ
RKLGLLLHDC IQIPLQLGEV AAFGGSNIEP SVRSCFEKAK GRPEIQVGHF LDWLSLEPQS
LVWLPVLHRL AAAETAKHQA KCNVCKDFPI IGFRYRCLKC FNFDMCQNCF FSGRLVKGHK
LSHPMQEYCT TTTSGEDVRD FSKVFKNKFK SKRHFKKHPR LGYLPVQTVL EGDSLESPAP
SPQHSILMSQ DMHSRLELYA SRLAEVEQRQ NCSSPDSEDE HHLIAQYCSS LNGDPSAQAL
KSPMQIMLAV DAEQQQELEA TIKELEQENR TLQEEYNRLR EARESRESST LSEDGGNISG
NIRDEEMLAE AKLLRQHKGR LEARMRILED HNHQLEAQLA RLRQLLDQSQ GDRSLASINS
SSRSTPITTP SSSQSSLPGG LGRYRFTPTA ESSQHLNGHS SGIVGTEETS ITAGDNTASS
ITTDKSKGNV GELFHIAGEV GQAVGSLVTV MTDQEGGVVE ESRH
//
