ID   A0A2T7P3K9_POMCA        Unreviewed;       733 AA.
AC   A0A2T7P3K9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Xaa-Pro aminopeptidase 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C0Q70_10559 {ECO:0000313|EMBL:PVD27983.1};
OS   Pomacea canaliculata (Golden apple snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX   NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD27983.1, ECO:0000313|Proteomes:UP000245119};
RN   [1] {ECO:0000313|EMBL:PVD27983.1, ECO:0000313|Proteomes:UP000245119}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD27983.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PVD27983.1};
RA   Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA   Zhang G., Qian W., Fan W.;
RT   "The genome of golden apple snail Pomacea canaliculata provides insight
RT   into stress tolerance and invasive adaptation.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVD27983.1}.
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DR   EMBL; PZQS01000006; PVD27983.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7P3K9; -.
DR   STRING; 400727.A0A2T7P3K9; -.
DR   Proteomes; UP000245119; Miscellaneous, Linkage group lg6.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   PANTHER; PTHR43763:SF4; XAA-PRO AMINOPEPTIDASE 2; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..733
FT                   /note="Xaa-Pro aminopeptidase 1"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015638179"
FT   DOMAIN          56..182
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          386..603
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          614..675
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
FT   REGION          674..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   733 AA;  80757 MW;  F0A31E9B8B2B42A1 CRC64;
     MLSEARLILA LSTASLCHGG PIAGEGGHRT KREAGQPTLA DRLNCSQGDR VNTTQRLADM
     RAAMRQLDID AFIILSDDAH GSEYPSERDE RRGFISGFTG SAGQAVVTLH QAALWTDGRY
     FLEAEGALDC NWIFMRSGDA NVPSISQWVI SELANTSGVV GADPFLVSNS QWQSFEKAFV
     QANITFKQVF KNPVDTAWGG YQPAPPMSNI TALPMEFAGK TWQDKITELR QSMTAKNADV
     FVVTSLDETA WLFNLRGGDI SYNPVFLSYA IVEKTSVRLY LLNKNERLTQ NATDPVTSIK
     LKEHLNTGDT GSCTGSSASC VEVVDYNETA IVEDVKALAT AGKKIWVTFV CNYAIFSAIP
     EASRIQDRSS IALAKAMKNQ VEREGMERCY IRDSLILIKF LAFLEKEIKN GHYWTEVSAA
     ERLKEMRLQG QYNRGLSFES ISGSGPNGAV IHYRPLNATN RQITTTEMYL LDSGGQYLDG
     TTDVTRTMHF GTPSSHEKEC YTRVLMGAID LANLVWPQGL YGREIDMAAR APLWQVGLEY
     NHGTGHGIGA YLSVHEGPGF ISLSKSSFNA QEELKPYMVF SDEPGYYENG KFGIRLETIV
     MVEPTSIKAP SNKTFYRFKP MTLVPFEPNL IDTELLTKSQ ITWLNKYHEL VWNTMKDNLT
     SEEERSWLWS RAQPIGEDTN STTPAATTVG SSPTGSTPAT TTVGNSPTGS SPLVTPITSA
     TVFLVAAVTS LYL
//