ID   A0A2T7P3T9_POMCA        Unreviewed;      1079 AA.
AC   A0A2T7P3T9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=WD repeat and coiled-coil-containing protein {ECO:0000256|ARBA:ARBA00015683};
GN   ORFNames=C0Q70_10673 {ECO:0000313|EMBL:PVD28092.1};
OS   Pomacea canaliculata (Golden apple snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX   NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD28092.1, ECO:0000313|Proteomes:UP000245119};
RN   [1] {ECO:0000313|EMBL:PVD28092.1, ECO:0000313|Proteomes:UP000245119}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD28092.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PVD28092.1};
RA   Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA   Zhang G., Qian W., Fan W.;
RT   "The genome of golden apple snail Pomacea canaliculata provides insight
RT   into stress tolerance and invasive adaptation.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GDAP2 family.
CC       {ECO:0000256|ARBA:ARBA00008355}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVD28092.1}.
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DR   EMBL; PZQS01000006; PVD28092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7P3T9; -.
DR   STRING; 400727.A0A2T7P3T9; -.
DR   EnsemblMetazoa; XM_025242708.1; XP_025098493.1; LOC112566492.
DR   Proteomes; UP000245119; Miscellaneous, Linkage group lg6.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   InterPro; IPR028041; WDCP.
DR   PANTHER; PTHR14897; WD REPEAT AND COILED-COIL-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR14897:SF5; WD REPEAT AND COILED-COIL-CONTAINING PROTEIN; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   Pfam; PF15390; WDCP; 2.
DR   SUPFAM; SSF52949; Macro domain-like; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          713..891
FT                   /note="Macro"
FT                   /evidence="ECO:0000259|PROSITE:PS51154"
FT   REGION          380..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          621..655
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        380..416
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1079 AA;  120258 MW;  03DEA8BEFBBCF99A CRC64;
     MSLYLQRFIQ NTVSFGLTVK ASSGSCASPS GAGGNGGSVR LGEFESVQSV HWSISVASET
     CYMAAVHQQN VTVWRVTGTA PRLNFKQMRK INVQVIPQGC LWNPVCDVLC LLSRQQCSFY
     FRHTQNRGSF AFPSLEKEKI SCGCWSQDGR RLVLGVGAAL LIYTWADVDS NISDFVPAAW
     CIPGALGSIT ALSSASSSTF VCASDQPLER LCKKKDVDAF LLPADLKETC DSLSIKDSLL
     HLQQNPKADM QDTAMLHVLK LPPDMRDPLV VAKVAIANML SPDLLCFQSE SQCVVVGSNT
     QSQFQIFALL DNHLVPAGHM SLAKDEKPKG MCNLPAALAS NAVGVLVLVG TAKPTDATFP
     SSSKKMQQFS SYHSQNLKVQ SSGALTKADS VRELKSQTVG ESRLQTRTSS YRGDRSTPRM
     KSSEPVKENS MEPMTVQENF MEPMTIRVSL SPEDSPVGLK KLVEEVNTTN RLQPSPSLET
     ELADFSHSSP KFLNTKLSHT FEINNNVHDR IEAATCKERK TETELFPAHS RMYSGHGETE
     PFHHDRMAEI ASGLHGVFTG VKVAPTDPSD LHTEINGAHH QQIQPHGESK EALSPLLVLP
     PGRDGAGGKL TDDKGSTCSS LNSSDSNYEM LERQIQQQKD QIDALQKKLG ELSVMVQETS
     CVFPVHYQNF SEPEFIHIKC VAGEKQAHRR FLLDNGRLQL EPVKLAFSLT TVELILADND
     KLSTLIFLAS GDPSKLLTVD GEEEHSPEDF EELSLMTFFL TLMHEGGGFS RSPVCKTGEA
     KLTKGYNLPA RYVIHTVGPR YNLKYITAAE SALFSCYRNT LQLCRENGIR SLGLSCIHTL
     GRGYPPEGGA HIALRTVRRF LEKYPDTLDT LLFVCTDDNL EVYRRLLPLY FPRSIKEEEE
     SIPKLPKDIG NEDGEPIIEE RQIRIIDKPT FAAYRSEGIK DFDETIDLNE RFMTSGAVDV
     GHHPFASMEE NPDKNKTKVL QGISTEEYRR AETRRRYKKN LKSFYIIHPT LWSKFATWFF
     TTFTASDIKR KVHSLNGVQY LYTKINPDQL DIPQFIHEYD IRINGPRYFV PEPESVDEL
//