ID A0A2T7PIS1_POMCA Unreviewed; 347 AA.
AC A0A2T7PIS1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=Autophagy-related protein 101 {ECO:0000256|ARBA:ARBA00018874};
GN ORFNames=C0Q70_04562 {ECO:0000313|EMBL:PVD33309.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD33309.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD33309.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD33309.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD33309.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATG101 family.
CC {ECO:0000256|ARBA:ARBA00007130}.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC {ECO:0000256|RuleBase:RU362109}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD33309.1}.
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DR EMBL; PZQS01000003; PVD33309.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7PIS1; -.
DR STRING; 400727.A0A2T7PIS1; -.
DR EnsemblMetazoa; XM_025231797.1; XP_025087582.1; LOC112560165.
DR EnsemblMetazoa; XM_025232459.1; XP_025088244.1; LOC112560542.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg3.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR012445; ATG101.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR023313; UBQ-conjugating_AS.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR13292:SF0; AUTOPHAGY-RELATED PROTEIN 101; 1.
DR PANTHER; PTHR13292; UNCHARACTERIZED; 1.
DR Pfam; PF07855; ATG101; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00183; UBC_1; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362109};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362109};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|RuleBase:RU362109}.
FT DOMAIN 26..170
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT ACT_SITE 108
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10133"
SQ SEQUENCE 347 AA; 40093 MW; 169068027513357D CRC64;
MIKLFSLKQQ KKDGDATAER GKKASAAQLR IHKDINELNL PKTCQVDFPD PDDLLNFKLI
ICPDEGYYRG GRFVFSFKVG QGYPHDPPKV KCETMVYHPN IDLEGNVCLN ILREDWKPVL
TINSIVYGLQ YLFLEPNPED PLNKEAAEVL QSNRRLFEQN VAKMYSEDKS KKWRNMTYTQ
EAKYSSGTLG FVDVDCDFID LTYVRLACDH LDHHLKREIS SFRDALRVTD GPQSGEICLE
FYQKKRARWP FQAECIPWEL WTLKMDVINL NSEHERNAHR QNLGVALAEK IMFVADNMSH
HQYVPKTPNQ NEVDLVFDTG FDIVQPYLFR ISHQEPGASV GFDLGQL
//
