ID A0A2T7PKQ8_POMCA Unreviewed; 3011 AA.
AC A0A2T7PKQ8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=MAM domain-containing protein {ECO:0000259|PROSITE:PS50060};
GN ORFNames=C0Q70_05252 {ECO:0000313|EMBL:PVD33990.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD33990.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD33990.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD33990.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD33990.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD33990.1}.
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DR EMBL; PZQS01000003; PVD33990.1; -; Genomic_DNA.
DR STRING; 400727.A0A2T7PKQ8; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg3.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd00112; LDLa; 3.
DR CDD; cd06263; MAM; 16.
DR Gene3D; 2.60.120.200; -; 17.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR PANTHER; PTHR23282:SF146; ENDOSOMAL GLYCOPROTEIN PRECURSOR, PUTATIVE-RELATED; 1.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR Pfam; PF00629; MAM; 17.
DR PRINTS; PR00261; LDLRECEPTOR.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00137; MAM; 17.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 17.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS00740; MAM_1; 1.
DR PROSITE; PS50060; MAM_2; 18.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..3011
FT /note="MAM domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015662991"
FT DOMAIN 25..203
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 205..377
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 390..547
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 543..697
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 699..857
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 876..1034
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1051..1152
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1154..1321
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1322..1377
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1457..1622
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1676..1837
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1848..2007
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2009..2173
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2175..2331
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2350..2520
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2522..2681
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2683..2839
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2876..3011
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DISULFID 1425..1443
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1437..1452
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1641..1653
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1648..1666
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1660..1675
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2848..2866
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2860..2875
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 3011 AA; 329581 MW; E51BCD657F06C59C CRC64;
MEGSSPLLLF LLFAAALAVS KGHMLDCNFE QDFCQWRQVT GADSLDWQRH SGSTPLSTTG
LSFDHTTGKN GSYAYVYFDS SNGIAGATAQ LYSPLLTVGR NNYMCLTFWY QMNGGHTGTL
TLYHNNTRLW ALSGGQGNVW LQAQDHNRGH FSRGELFKVC SRSELAQACV CRPHIVFEAQ
REGFASGDIA IDDILMKNGA CVDADSCDFE KDLCLWTNAH DRKDELDWLR VQGSTVARST
GPSNDHTQDT SSGHYILLEP SPNYAEEAYA LLVSQIFSAS PGNDYCFSFW YYMSDEGAST
LTVLIFSNVS RDVISPETAL WQHPNGNGDQ WIFAEVSIST DYTMEPFQIA LKVQLERVTM
APIAVDDTAL IFGYCPTQFD FAPTSDISLI YCDFDHGSTC SWNQSTSDLF DWTLASHSTP
TAGTGPSDDV SGGGSYLYLE SSPQKVGDKA DLVSSLLPPT DGLSCFNFYY HMFGPTIGTL
SVYIAVGVSE SLKWTLSGSQ GDEWKDAHVT ISSNSHFYVN YHQRSVGGSQ GDIAIDEVYF
EPQACPEING DMCSFVQLSN GSLHWINTNG SNHNGINVDH TTGSETGHYI TLTNSSSTNN
SATMVSPMYA PSSGECLQFY YHIHGNNGGS LKVQLHLKTS ESIIWQMQGE QGDDWKIAQV
TIKTLTKYQL SFSGWMLPGS GDVSLDDISI LPFPCAEPGS CDFETDFCTF TNSKTDQFDW
ILGFGDTKSL YSGPSTDHTT GTVEGHYIFI DSTTSLPGDK AQLVSETLHP TPGSCLVFYY
NMNGAGMGSL NVYKSTQLSQ KLIFNQTGHH ANAWLQSSVN LTSVTPYTII FEGVKGANNT
SDIALDDISV SQGACGQQNG TGTPGITTTP LSIPNLGCDF ENGICQWTQD TSNQFNWTWQ
QGSTATADSG PRFDHTQGNI RGHYVDVDAS HAANATARLR SPQFSNTGST CATFWYHMYG
ADVNKLNLYL ASPGKPGSQV WTKSGNQGFM WQYAEVEVGA VSSAQLIFEA VCGTAYMGDI
ALDDISIISG PCPAPGKDLC HFIYLKPVNF GGEALLLSKP YNPTFGSCLT FWYYQRGGDV
GTIFVSIVPV GEEITPSSIW RMDDDQGTQW HLAAINIENA EQFQVVFKGS LSGYGGGIAL
DDIRMSPISC QVLADCDFEQ GGICTWTQSQ NDDFDWLVNS GETASLDTGP PSDHTTGTES
GEYIYLPSMA PLHPGYKAIL ISQIIPLYDL PDLCFTFWYY MWGSRAGTLN ISYHIQGAFS
DEPVITFTRT GNQGNNWIQG FMDIPQPWNA ITIFIMGSIG NGDKGDIALD DFKLYSISCD
QGDCDFNDDN CQWTEASNSI WQWSLGNGQS NASRAVPKYD HSGSTTVDDY NDDDTFLDKD
KIHIQGYTAL TTSFQGIVAV DDVQFENCNF PVPGNCDSSQ TQFHCNSSAC IPMAAVCDFT
DDCGDGSDEA SCGTYPSRTD FEQSLGAWYN DQSGSDNFDW IRMHGSTSTS GTGPSRDHSR
GTSSGYYMYI DSSPPSKPGD KAWLLSIDAF NPTLGSTCAL RFYYHMYGAA IGNLNIYTRI
SLHGNLKQIL SLSGNYGDAW MRKDIILQEK ELFQIVIEGV VGNGYLGDIG IDDISMTSDC
QVSKVSLPSG STPLPTQPAP CSANQFACDG YRCIPRSQVC DFHKQCSDGS DELMCGDCTF
EAGLCGWRDH STGQFAWVRK SLNESASTGG PSSDADGGAQ YIIVQPTMGV TQDPARLMSP
VLNASAAMCC MNFSYHMFGS SAGNLRILLQ QTIDIGTDNG IDLWHYSGTA GNAWQQYSVR
IGQIDYPFVI TFSSLPTPGF GRYDVAIDNI AFSDCQNEKI FNHTEVSMDC SFDLGLCGYS
QVQTDNFDWS LTDISTPTEG TGPDRDHTSG TGCYIYIETS TPQKPGDVAD LTSPLQAPTS
PEGKCLKFWY HMFGAHVETL NVFIQQDSNR TLIWTRSNTQ GNIWRQALRT IVSYQSYKVI
FEGVVGVSFL GDIAIDDVSL VDEPCPPSLE CDFEADFCDY TQSTDDQFDW IRHANNLSQV
NTGPSWDHTA LNREGYYAYL TTGPPHKAGD RAVIVSPVQQ RSLISQCLTF WYQMYGFPSV
GQLNLYIISN GTRSTSPVFS VAGDHGSIWI QAAYTLPPPK ASWQIMIEAV VGQSDAGDIA
IDDIKIQEGD CPPPGSCNFE VDTCSYYNIE GYGMDDFDWL RSAGGTVVAG TGPAVDHTSD
SDAGFYMYMQ ADTHSMGQRA SFSSSPIPCS PQMCISFWYH MYGQGMKELV IIFECQLSVN
LVIVSVSGVF ALTTIKFQLT FQLIFDGTVG NGSRGDIAID DVSVKPGNCT GPPATDNPGI
SQVTYAPTKY DCNFDQASIC NWIQDITDNF NWTLHHGATA SLQTGPSYDH TQQNINGYYI
YTEASHQPAN ATARIMSQTV TINNTGLCVH FWFHMYGSSI GLLNVYAQQG KNLGNPLWTR
SGEQGDKWIS ATLFLTPQGL SPLQNQTTIV QIVFEGVLTR GYQSDIALDD ISFNNGNCPT
SVSCSFDSDD ICGYLQETIA NYSWTRQRGH TPSSGTGPAA DHTYGTMSGY YMYAEASKGN
PGENANLLSP VQPATTGKCL HFYYHMSGTG MGTLMVSIRA RAVSTVIWRR FSDQGDDWHT
AQVSINSNFQ YQVEFQAVRG STYQSDIAID DVELQDGLCS LPASCDFEQG QCAWSNDDAD
DDFDWIRSQG STITANTGPT SHYMYIEASQ PRKPGDKARL HSEILNNSSH PQCLTFWYNM
HGAGMGTLSV YKNLVSRTSG LIQLWTLSGD QGAQWQKASV PVHDNKKEFM LVFEGVVGSS
YLSDMAIDDV SLTDGDCSSS SQPSKFTCRN QQTVTSDKVC NFVKDCSDGS DEVQCGNCTF
EVDLCGYNDI SKGSFRYLRT SNSTSTKSLP IPFDHSYNKN SGYLLYVDTS RGTFNSLATL
ASPVLHQSSP ACQLYFYYFI IGSAGAGQLQ VSVMTGDTKT IVWQLRTSSV TNQWLLAVAD
IGALMETSRF T
//
