ID A0A2T7PNS4_POMCA Unreviewed; 871 AA.
AC A0A2T7PNS4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51193};
GN ORFNames=C0Q70_06354 {ECO:0000313|EMBL:PVD35073.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD35073.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD35073.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD35073.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD35073.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC DDX11/CHL1 sub-subfamily. {ECO:0000256|ARBA:ARBA00008435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD35073.1}.
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DR EMBL; PZQS01000003; PVD35073.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7PNS4; -.
DR STRING; 400727.A0A2T7PNS4; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472:SF41; ATP-DEPENDENT DNA HELICASE DDX11-RELATED; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119}.
FT DOMAIN 41..388
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 195..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 134..164
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 196..215
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 97950 MW; FA4BBEF5F91FCFEB CRC64;
MADNFEDDDD ELFSVIVDEE CGKETTTQKV AEKENFGDCS VPTTFPFPFE PYQIQTDFMR
QLYICLQEGK VGIFESPTGT GKSLSLICGA LTWLKDFQDN QRKELDAFLS ESTKTNGYSQ
GGGGFDWVTE FSKRKEQEDR LSRAKQEQEL IEQREKRLKN VQSSSKVTRG KRKFAQLEDD
FSDLLKGSSI ETQKAFNEDY ESDEEKSAEW KENENDEDAH VTKNLCINEA VRKLKSVSFI
NDRCLELQQK KSKKNPGCPY RKQEILEDFR DRALLGLCDI EQLTTLGRET KTCPYYGSRL
AIPSAEVVVL PYNTLLHKST REASGVKLAG NVVIVDEAHN LLETVNSVHS VEVTGAQILR
AHSQLSQYEV KYRSRLKAKN LMYVKQILFV LSNLVKCMGG KTGVPADKQN TGKSDVNLMT
INNFLFEAKI DNLNLFKIRG ILSPQSDQQE EKYQVAEVIP AMPVAVKETA TFGVSMFLKN
IGKAKTSDPI KEDITVDVVN RNKSTPVLNS PLMHIESFLQ ALTTANDDGR VVLSKQMLLS
QSGIKFLLLN PAVHFADVLQ EARAVVVAGG TMQPISEFKD QLFFAAGLQP DKLLEFSCGH
VIPPDHLLSL TLATGPTGRQ LDFTFQTRDD PHLLEELGRL VVNLCSVVPG GIVLFFPSYD
YEQLVSVSWE KSGILGRIEA KKKIFREPKS AIQVEHVLTQ YGDCIKKCQC RTTGGPTGAI
LMCVVGGKMS EGINFSDDLG RCVLMVGMPY PNLRSPELKE KIDYLNSNFP KDEAGRPAGQ
VHYENLCMKA INQSIGRAIR HREDYAVIIL ADQRYSRTSV SSKLPGWIAK HLYKMDAFPP
ALARVSKKEE NDFQWWMLLL MFATDDFRDH L
//
