ID A0A2T7PUH8_POMCA Unreviewed; 1493 AA.
AC A0A2T7PUH8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=C0Q70_04043 {ECO:0000313|EMBL:PVD37050.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD37050.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD37050.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD37050.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD37050.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD37050.1}.
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DR EMBL; PZQS01000002; PVD37050.1; -; Genomic_DNA.
DR STRING; 400727.A0A2T7PUH8; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg2.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 10.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 8.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF14670; FXa_inhibition; 6.
DR Pfam; PF00053; Laminin_EGF; 5.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 31.
DR SMART; SM00179; EGF_CA; 8.
DR SMART; SM00180; EGF_Lam; 21.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS00022; EGF_1; 15.
DR PROSITE; PS01186; EGF_2; 7.
DR PROSITE; PS50026; EGF_3; 11.
DR PROSITE; PS01187; EGF_CA; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1493
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015626413"
FT DOMAIN 50..85
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 128..168
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 252..292
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 380..420
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 480..511
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 524..556
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 745..775
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 783..818
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 960..990
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1371..1401
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1451..1486
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 75..84
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 501..510
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 527..537
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 546..555
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 765..774
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 808..817
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 980..989
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1391..1400
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1476..1485
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1493 AA; 160367 MW; 5B4D88D0914E2725 CRC64;
MLLLFLLEVF NCFTWRLQQS SMPPMSGNPP CDDQREGSHL TGPWQCLCGG RGQCNNAMCH
NGGQCRGGYY PSCACPPGFQ GPQCQYDVNE CSNNNGGCER DCQNTVGSYK CRCSTGFELA
EDMKACVDVD ECVDHNGGCQ HKCVNTYGGF HCECPKGQRL HADGRTCISV SGCSVSNGGC
EHVCVDGYNG HYHCRCRSGY TLGDNGKTCH EADPCRENNG GCEHKCVNDR GRAICQCFSG
FSLSADGRSC QDINECEQQN GMCLQTCINT KGSFVCTCTP GYQLGVDGRS CYRIEMEVVD
FCAIGNGGCD HKCQHSREGP ICSCRRGYSL MADGKACRDI NECEEGEKCC SDYCNNNPGG
YTCSCRQGFL LSRDGCTCDD IDECLGNNGG CEQICVNSQG SFSCVCNQGY TLSIDGQRCL
PMESRLTDRG PQRGDLPKIR FETTPRPIIP ATDHNILSQE LLETESKYTC IPGTFGPDCG
YMCTNCQNGA QCTEARDGCV CPAGWQGTLC DQPCSEGTFG EGCNRMCTRR CQNGGSCHPV
TGRCKCPPGV KGENCEDGCP PGYYGEACDK LCLHQCSSGY CNRIFGICEC RLGWFGPSCN
LPCPPFTYGS NCMEQCNCVT KNSKGCNSET GECQCKIGYH GDRCEDECPE GRYGDGCQHR
CSCPVGTKCD PMSGYCLRDC PAGWTGSRCN EPCPHGKHGK NCKLSCRCHG NACDPETGKC
VCEPGRMGKR CRRTCPEGSW GINCKNKCTC ENGATCDTVT GECLCRDGWY GPHCREECPE
GRYGPQCLMR CMCENNASCN PADGRCTCKA GWTGQICDRA CPPGMYGENC VLRCNCLNSA
ECDPVTGECL CAPGWRGTSC AQPCQDEMYG PGCSRKCRCQ NGAECDHISG ACTCAAGWRS
IYCEKACPEG FYGIECQSIC NCGTGSTCDH VTGKCACPAG YMGILCDQRC PPGTWGQDCR
RDCECDNDAN CEAISGQCIC PPGFRGARCE EPCPHGTYGQ NCLYRCFCMH DSTCNHIDGT
CNCTNGWMGD ACERGCASGR WGPNCAMECE CVHAMSCDST NGQCYCDVGY TGLRCNRTCP
VGSYGKDCKE TCMCANDAEC DHKSGKCTCK DGWVGDRCER ACSFGLYGKD CKDRCNCTLG
DPCYHVTGQC SCPAGLTGSA CEESGFQLDS SVNLVNSDPE GCSEGSYGPN CDRVCNCENE
GTCDVSTGNC VCPDGFVGPT CGQRCPENRY GENCTGICTC QNGARCNKGR ASASVSLATQ
EKPAKTVRDG EGGWACPDGT FGLNCEEKCQ CSHGNCDHVT GACSCHLGWT GKTCSEGCPP
ERFGPDCAHS CMCKNNGSCD SASGCCSCTP GFYGQVCEIE CPEGTHGTYC TDRCDCVNGA
KCDPRTGQCK CPTGLTGDRC EKSCPKGRYG MNCRQECSCG ETDCDSVSGE CLCQPGFTGD
HCMKACPEGR FGPNCEYQCN CDNNGLCDPQ SGTCLCPEGW VGARCQTAES EWL
//
