ID A0A2T7PVF7_POMCA Unreviewed; 1100 AA.
AC A0A2T7PVF7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C0Q70_00005 {ECO:0000313|EMBL:PVD37415.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD37415.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD37415.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD37415.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD37415.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD37415.1}.
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DR EMBL; PZQS01000001; PVD37415.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7PVF7; -.
DR STRING; 400727.A0A2T7PVF7; -.
DR EnsemblMetazoa; XM_025231817.1; XP_025087602.1; LOC112560179.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg1.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119}.
FT DOMAIN 1..89
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 787..1100
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 394..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 266..315
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 396..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1100 AA; 123320 MW; 8FC2003F5370DC66 CRC64;
MDDPLQIYAF MFDQNIGCAL AALYEEWAGF LERLGHASKA DQIYLEGIKR EAQPIDLLKH
KHQEFQIRMI RGMSRESLAE TEEGDMEEQR IVLGQLKADR KNRVGTMRTG AIRMSATRSQ
VGLQSASQSS TQVQRTVQVF QDENQAPSLL QTGEWKTVPC REQTNRENDL VPDIWTKARV
HQKKGVISCT PAPLTFKVHE DQEMVQPPRA PVLDTYALSS RKVEKPVHLL DPICKSESSN
VERPAYCKDK IYCGTQEFSF EEIRALRVME RRRQKKLQEE RDLMEKQLAE MRLMRDQMCK
DMERMKEEAL LLNQRQPTAT HCMQLQLSAQ DNAFHSSSSS SFNTMDFLSS SLMPTRNRQS
LRLSQISSTV QVGAPSGHAS TQLTPIHDML ASDNLERSCG SGTQFSLHQS HSDGRTPENN
TSKHSLHSVS PTINTREALQ MVQGMYNATL DCEKMVWTQE DITEATAPVP PVPVEIYDET
KQNPSTSSIP IFCDQENRLP GLVFSQIKKD GPSLNLANVR KALPEKPMST SSSLIRGGQF
NTEDFMQEGT ELYNNLTLTL APVGSQDSFS AAARLASTPF GPSTNNSHGL PTFSLDSSKS
IDPGKENGEM WKGKCHTEEQ QSVSQCPDPH QQQTFLGHRT TAGNNHLSPI TEGSTEGSTE
ESKSHAASSL GGSRTFFSTL AKTSAGHDNQ GDFLSMTSRD YLNEESTEQH IIDTTAYIPL
EQYEKAEALL STSVCLDTHN PFDEATTRTL LSSVQPPISC RANYIACHQH VPNFSNCHFI
NLGEDTYQLA GLIGEGGFAK VYRATNFGNN FDDLSDDEMD SPSCVIKVQK PAAPWEFYIC
SVVHEQLSKL QIPMDIRPSL QEITHGYFYD DGSCLVSELC PLGSLLTLAN SLKQDKKLLA
DLEPLAAFLA VQLLNIVHGL HRCNIIHGDI KPDNILLLQL PQVNKGSDID KVFGHQTQVL
RLVDFGQAID MSLYPPGTTF LAKVKTSGFQ CIEMMTDRPW TFQTDMFGLV GSLHVLIFGQ
YMKVYSSQGH WYITSSFQRK WKVDLWKKLF YQLLNIPDCD HQPDLLALSH QFQQHFVDNL
LCDFRPLMAR VTAVCQADSL
//
