ID A0A2T7PXN3_POMCA Unreviewed; 384 AA.
AC A0A2T7PXN3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN ORFNames=C0Q70_00802 {ECO:0000313|EMBL:PVD38191.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD38191.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD38191.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD38191.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD38191.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD38191.1}.
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DR EMBL; PZQS01000001; PVD38191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7PXN3; -.
DR STRING; 400727.A0A2T7PXN3; -.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg1.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR PANTHER; PTHR11848:SF283; TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 259..384
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 44..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 384 AA; 42499 MW; AFA793EABFE9890F CRC64;
MGCESLSAPI RYAQMPASGL EPASPQTGSL RGIRFFQVAI DTDSDASDGW DHEGQEQLPG
VETVPHSGLQ RHQPAVVRGT RLSRRTPPLH IGGTRPPHLP GARPPRHRVR RSKTPDPGPP
APEVPERTVE NEVEEEGPDD GVQVLEVSIA TVFQPGHRTP ATDMDIDVDP EHDQGPLLVV
FSRDTHRHRQ RELQALIGHE PESEDLEATS VEHAPGTGAA NEFSAVRKYR DTRAMVARSN
LTDGPDVEEN DVPLQRFRRE KRKAQQLQKD AAVRRLPGDQ LAPVDYCPTW LSVSWKILMA
ELLFSLQAFE CVGKCYVPIG SHLSPTKHAI IQTLMHAAHP KRASRACCVP TKLDPISILY
LDENGVITYK YHYDGMVVAE CGCR
//
