ID A0A2T7PYE3_POMCA Unreviewed; 737 AA.
AC A0A2T7PYE3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=guanylate cyclase {ECO:0000256|ARBA:ARBA00012202};
DE EC=4.6.1.2 {ECO:0000256|ARBA:ARBA00012202};
GN ORFNames=C0Q70_01035 {ECO:0000313|EMBL:PVD38420.1};
OS Pomacea canaliculata (Golden apple snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Architaenioglossa; Ampullarioidea; Ampullariidae; Pomacea.
OX NCBI_TaxID=400727 {ECO:0000313|EMBL:PVD38420.1, ECO:0000313|Proteomes:UP000245119};
RN [1] {ECO:0000313|EMBL:PVD38420.1, ECO:0000313|Proteomes:UP000245119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZHN2017 {ECO:0000313|EMBL:PVD38420.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PVD38420.1};
RA Liu C., Liu B., Ren Y., Zhang Y., Wang H., Li S., Jiang F., Yin L.,
RA Zhang G., Qian W., Fan W.;
RT "The genome of golden apple snail Pomacea canaliculata provides insight
RT into stress tolerance and invasive adaptation.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVD38420.1}.
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DR EMBL; PZQS01000001; PVD38420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7PYE3; -.
DR STRING; 400727.A0A2T7PYE3; -.
DR EnsemblMetazoa; XM_025238993.1; XP_025094778.1; LOC112564287.
DR Proteomes; UP000245119; Miscellaneous, Linkage group lg1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF01094; ANF_receptor; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW cGMP biosynthesis {ECO:0000256|ARBA:ARBA00023293};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000245119};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 457..737
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 737 AA; 83890 MW; E6C00ED0898A4630 CRC64;
MLLLWSLSII GYEAQTQKEN LTIGYITSMD GPPLVQAEGR SISGAMSLAV NVINENPSIL
PNHTLRFIFS DNHADPLASV HVLTEQWRAQ AIAFIGPEGY CETEARVAAS WNLPMVSYKC
SDPVVSDKSR FPTFARTQPS SSLSGSSVVR LMLYYGWRKF SIVVELNDLM IEQDRSSRSW
PNIYVLFTCT KAFQDMVNFL QEMGLTDTGE YVVIGIRDDE TYDETKASSL VIPGTRLLLR
LLSKLLCLKT WCLKTIFCFN KQNYTPLLQI SIFGAYLYDA VQVYARALHE VLISGGDIRN
GTDIFNRIKD RTFQGIQGHE VYIDENGDAE ANFTVLALRP DTGIYGYAMR PIGRFLRDTL
DRHNLTFIED VKVYGEFIPL DEPECGMKGR NAGERVNCEG RGARMSQSVF TIAIKHKKVF
FDYELLFFRN WRYEQELASL IWKIDPKEIQ KKPETAYSAI SIMSNNGPHN TLTMNSEVIQ
EQRFTEIGVY RGSLVALKPI HTRHHIDVTR DMRLELKQLR DIRHDNIVHF IGATVEHNCL
QIVTDYCSKG SLEDILENAD LKLDHMFTAS IVSDILKGMM YIHSSPIVCH GELKSSNCLV
DSRWVVKISD LGLKRFKARK MIPDIGIHAK YKRLLWTAPE ILRKNIPLPL GGTQRGDVYS
FGILLYEIMC RKGPYGDCHL SPREIISRVT RGPVDGIAFR PNTSQLTSCD TYILDTMRAC
WDENPDLRRT SRPVEDF
//
