ID   A0A2T7T8P7_9ACTN        Unreviewed;       345 AA.
AC   A0A2T7T8P7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=IMP dehydrogenase {ECO:0000313|EMBL:PVE11544.1};
GN   ORFNames=Y717_03025 {ECO:0000313|EMBL:PVE11544.1};
OS   Streptomyces scopuliridis RB72.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1440053 {ECO:0000313|EMBL:PVE11544.1, ECO:0000313|Proteomes:UP000245992};
RN   [1] {ECO:0000313|EMBL:PVE11544.1, ECO:0000313|Proteomes:UP000245992}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RB72 {ECO:0000313|EMBL:PVE11544.1,
RC   ECO:0000313|Proteomes:UP000245992};
RA   Olson J.B.;
RT   "Annotated genome of Streptomyces scopuliridis.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVE11544.1}.
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DR   EMBL; AZSP01000137; PVE11544.1; -; Genomic_DNA.
DR   RefSeq; WP_030353945.1; NZ_JOEI01000019.1.
DR   AlphaFoldDB; A0A2T7T8P7; -.
DR   STRING; 1440053.GCA_000718095_04955; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000245992; Unassembled WGS sequence.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245992};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          26..128
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          178..290
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   345 AA;  36552 MW;  DFABF644DDDFF3E5 CRC64;
     MRATFMYGPG DVRVENAPDP VLRQPTDAIV RIVRACICGS DLHPYHNIPA SEQGTPMGHE
     FLGVVEELGS DVSGLRRGDL VVAPFAWADN TCDFCREGLH TSCRHGGFWA AGGIGGGQAE
     AIRVPQAQGT LVKLPVGEDS ALLPSLLTLS DVYGTGYHAA KMAKVNPRTT VTVIGDGAVG
     LMAVLSAKRL GAERIILMGR HKDRTDLGRD FGATDVVAER GEEGIAKVRE LTGGDGTHTV
     LEAVGYMSAY EMAVGVVRPG GVISRVGVPQ YEDAPIGFGS LFGPNITLNG GPAPVRAYID
     ELLPDVLDGT VEPGRVFDRT IGLDEVPDGY RAMNNREALK VLVRP
//