ID   A0A2T7TM91_9MICC        Unreviewed;       376 AA.
AC   A0A2T7TM91;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Type III polyketide synthase {ECO:0000313|EMBL:PVE19136.1};
GN   ORFNames=DDA93_04800 {ECO:0000313|EMBL:PVE19136.1};
OS   Arthrobacter sp. Bz4.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=2171979 {ECO:0000313|EMBL:PVE19136.1, ECO:0000313|Proteomes:UP000244710};
RN   [1] {ECO:0000313|EMBL:PVE19136.1, ECO:0000313|Proteomes:UP000244710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bz4 {ECO:0000313|EMBL:PVE19136.1,
RC   ECO:0000313|Proteomes:UP000244710};
RA   Goncharov A., Nikolskiy P., Shidlovsky F., Kolodzhieva V., Zueva L.,
RA   Masharskiy A., Suvorov A.;
RT   "Putative ancient Arthrobacter sp. strain from the intact mummy of late
RT   pleistocene steppe bison (Bison priscus bojanus).";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVE19136.1}.
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DR   EMBL; QDAE01000004; PVE19136.1; -; Genomic_DNA.
DR   RefSeq; WP_024476268.1; NZ_QDAE01000004.1.
DR   AlphaFoldDB; A0A2T7TM91; -.
DR   OrthoDB; 9786288at2; -.
DR   Proteomes; UP000244710; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244710}.
FT   DOMAIN          7..217
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          236..373
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        157
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   376 AA;  40634 MW;  BA851480E2B2EAC7 CRC64;
     MTVIMRSLET AVPETVMVQS DVRDVFAAQP GLNRLGTRLV GAAFDSSGIN TRYTAVKEMT
     LDAPSENPVF FDSAERRILS PSTKVRNEVY AEEGTKLFVE AADKALTAAE GIEPADVTHV
     ITVSCTGFFN PGPDYKVVRA LGLSPAVQRY HLGFMGCYAA FPALRAAKSF CEAEPDAVVL
     VVAAELCSLH VRSSNNPDTI VGSSLFADGA AAAVISAREY EATAPALSLD FFETVLTPVG
     EESMAWNIGD EGFEMVLGTY VPHIIDEHIV GALEPLLARD ETLADKQYKD IEHWAIHPGG
     RSILDKVEAK LDLKEDQLVP ARETLRDYGN MSSATVMFVL KHILEQPFDG ADERICSMAF
     GPGLTVETAL FTKVGP
//