ID   A0A2T7TN16_9MICC        Unreviewed;       622 AA.
AC   A0A2T7TN16;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=SLH domain-containing protein {ECO:0000259|PROSITE:PS51272};
GN   ORFNames=DDA93_03925 {ECO:0000313|EMBL:PVE19410.1};
OS   Arthrobacter sp. Bz4.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=2171979 {ECO:0000313|EMBL:PVE19410.1, ECO:0000313|Proteomes:UP000244710};
RN   [1] {ECO:0000313|EMBL:PVE19410.1, ECO:0000313|Proteomes:UP000244710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bz4 {ECO:0000313|EMBL:PVE19410.1,
RC   ECO:0000313|Proteomes:UP000244710};
RA   Goncharov A., Nikolskiy P., Shidlovsky F., Kolodzhieva V., Zueva L.,
RA   Masharskiy A., Suvorov A.;
RT   "Putative ancient Arthrobacter sp. strain from the intact mummy of late
RT   pleistocene steppe bison (Bison priscus bojanus).";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC       ECO:0000256|RuleBase:RU003355}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVE19410.1}.
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DR   EMBL; QDAE01000003; PVE19410.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7TN16; -.
DR   OrthoDB; 9790784at2; -.
DR   Proteomes; UP000244710; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07496; Peptidases_S8_13; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR034176; Peptidases_S8_13.
DR   InterPro; IPR001119; SLH_dom.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51272; SLH; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00136; SUBTILASE_ASP; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000244710};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          496..563
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   REGION          225..252
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          382..405
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        201
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        252
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        432
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   622 AA;  64349 MW;  19605B5CB97F0BB1 CRC64;
     MSWWSLDLAL KELVMTFGPS PRHPKSSWLT RSIASAAAAA LLAGSITALP AFAGQQSDKT
     AGVAEALTTD TNPADHPADR FIVKFDGNGD GTSERGRTYQ NTVNSLGIPV TEVGVTVDGA
     TVVEATEDLT AEQSDGVVAA LESRGDVEYA EVDVFMQPTA IAPDDDLYDS QWNLFEAEAG
     MRVDSAWERS TGAGVTVAVI DTGITEHSDL AGNIIPGYDF ITSPQIAGDN DGRDSDPTDE
     GDQCNSDPSS WHGTHVAGTI GAVANNSQGI AGVAYDSQIQ PIRALGACGG YTSDVAAATL
     WAAGGSVPGL PLNPTPAKVI NLSLGGAGTC GTTFQTAINY ANSQNAVVIT AAGNENTFAK
     YTTPANCNNV VVVGATGREG NKANYSNHGP EVDVSAPGGD ASTGRSSAIL STLNSGAAGP
     ETESYGYLQG TSMATPHVAG AAALMLSVDP SLTPAQVEAQ LKATSRPFPG VCYTGGCGTG
     LVDAAAAVKA VAPAVNPQPF SDVPVGMKFQ REMSWMAASG ISTGWTEFDG ARAYRPLTAV
     NRDAMAAFMY RMAGSPAFTP PTRSPFADVD TSQKFYLEMA WLASTGISTG WAGPNGTKTY
     RALTPVNRDA MAAFMYRFSE DY
//