ID A0A2T7UWI0_9RHOB Unreviewed; 569 AA.
AC A0A2T7UWI0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:PVE48929.1};
GN ORFNames=DDE23_00540 {ECO:0000313|EMBL:PVE48929.1};
OS Pararhodobacter aggregans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pararhodobacter.
OX NCBI_TaxID=404875 {ECO:0000313|EMBL:PVE48929.1, ECO:0000313|Proteomes:UP000244810};
RN [1] {ECO:0000313|EMBL:PVE48929.1, ECO:0000313|Proteomes:UP000244810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D1-19 {ECO:0000313|EMBL:PVE48929.1,
RC ECO:0000313|Proteomes:UP000244810};
RX PubMed=21959289; DOI=10.1016/j.syapm.2011.08.006;
RA Foesel B.U., Drake H.L., Schramm A.;
RT "Defluviimonas denitrificans gen. nov., sp. nov., and Pararhodobacter
RT aggregans gen. nov., sp. nov., non-phototrophic Rhodobacteraceae from the
RT biofilter of a marine aquaculture.";
RL Syst. Appl. Microbiol. 34:498-502(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVE48929.1}.
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DR EMBL; QDDR01000001; PVE48929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T7UWI0; -.
DR OrthoDB; 3178130at2; -.
DR Proteomes; UP000244810; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000244810}.
FT DOMAIN 7..550
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT REGION 457..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 61241 MW; BBB3E52DE67FD623 CRC64;
MERQEVDVLV VGSGAGGLSS AVAAAHRRLK VLVVEKEPVF GGTTARSGGW MWIPGNGPEL
RAGIEDNAEK ARIYLQHEAG AHFDAERVDA FLEAGPKAVQ FFEENTALQF DLGPFFADYH
PDAPGGMDGG RSIVARPFDG RELGPEIRRL RPPLQEITFL GMMIGSGKEL LHFFNVMRSP
VSAFYVGKLF LKFVRDMAFH GRPMRLMNGN ALAGRLAKSA FDKGVPIWTH APVRSLIRDD
QGRVIGARID RRDGPVEVIA RKGVVLAAGG FPQDIARRKA LMPHAPNGYE HVTPAPPGNT
GDGLRLGESV GATVDTSLPH AAAWVPISRP VRADGTLGTF PHFVDRSKPG VIAVTRSGRR
FVNESNSYHD FCQAMVARNR EEAGEGAEPA AWFITDHRAF RKYGLGFAKP APVPYKALIR
DGYLLQGRTL RELAAQFGAD GEQLERTVAE FNTHAARGED PAFGKGTTSY NRSLGDPEHG
PNPCLAPIKD GPFYAVRLYV GDLGTFAGLK TNANAQVLDE EGRPLEGLYS VGNDAASIMG
GNYPGGGITL GPAITFGYIA ARHMAGGND
//
