ID A0A2T8F6P4_9ACTN Unreviewed; 383 AA.
AC A0A2T8F6P4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Pyridoxal phosphate-dependent aminotransferase {ECO:0000313|EMBL:PVG81369.1};
GN ORFNames=DDE18_17935 {ECO:0000313|EMBL:PVG81369.1};
OS Nocardioides gansuensis.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2138300 {ECO:0000313|EMBL:PVG81369.1, ECO:0000313|Proteomes:UP000246018};
RN [1] {ECO:0000313|EMBL:PVG81369.1, ECO:0000313|Proteomes:UP000246018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSJ-1 {ECO:0000313|EMBL:PVG81369.1,
RC ECO:0000313|Proteomes:UP000246018};
RA Wu S., Wang G.;
RT "Genome of Nocardioides gansuensis WSJ-1.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
CC {ECO:0000256|RuleBase:RU004508}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVG81369.1}.
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DR EMBL; QDGZ01000008; PVG81369.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T8F6P4; -.
DR OrthoDB; 9804264at2; -.
DR Proteomes; UP000246018; Unassembled WGS sequence.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR CDD; cd00616; AHBA_syn; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000653; DegT/StrS_aminotransferase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR30244:SF34; DTDP-4-AMINO-4,6-DIDEOXYGALACTOSE TRANSAMINASE; 1.
DR PANTHER; PTHR30244; TRANSAMINASE; 1.
DR Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR PIRSF; PIRSF000390; PLP_StrS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:PVG81369.1};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR000390-2,
KW ECO:0000256|RuleBase:RU004508};
KW Reference proteome {ECO:0000313|Proteomes:UP000246018};
KW Transferase {ECO:0000313|EMBL:PVG81369.1}.
FT ACT_SITE 186
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-1"
FT MOD_RES 186
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-2"
SQ SEQUENCE 383 AA; 40465 MW; FE9023898B069731 CRC64;
MSSTRNVALG QPTVGEEEIE ALREVFASGW LSGAGPTCVA FEKEFAVTAG TAHALATSNC
GSALHLALQV LGAGPGDEVI VADYTFPATG HAVVWTGATP IFADVRPDIG TIDVDAAAAL
VTERTVGIIA VDLVGQPADY DELAALARKH GLWLLEDAAC SAGATYKGRP AGSLADLAAF
SFHGRKGITS GEGGALVGDD TDLMDRARKL HTYGIAPAVS REGQSALAVP EFDTAGYNYR
MSDVQAAIMR VQLRRLPDLL ANRTRAAEGY AERLAGVEGI SLPVLLDDRT HPWQSYLVTA
QDGVDRDRVV MALRERGVGS NIGTYSSHVQ PVYGATRDCP VAARLFRTQF ALPMHANLTD
DDLDHVAEQL REVLAAAEVR TSA
//
