ID   A0A2T8F8I8_9ACTN        Unreviewed;       828 AA.
AC   A0A2T8F8I8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Nuclease {ECO:0000313|EMBL:PVG82044.1};
GN   ORFNames=DDE18_15270 {ECO:0000313|EMBL:PVG82044.1};
OS   Nocardioides gansuensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=2138300 {ECO:0000313|EMBL:PVG82044.1, ECO:0000313|Proteomes:UP000246018};
RN   [1] {ECO:0000313|EMBL:PVG82044.1, ECO:0000313|Proteomes:UP000246018}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSJ-1 {ECO:0000313|EMBL:PVG82044.1,
RC   ECO:0000313|Proteomes:UP000246018};
RA   Wu S., Wang G.;
RT   "Genome of Nocardioides gansuensis WSJ-1.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVG82044.1}.
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DR   EMBL; QDGZ01000006; PVG82044.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T8F8I8; -.
DR   OrthoDB; 1016457at2; -.
DR   Proteomes; UP000246018; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd10283; MnuA_DNase1-like; 1.
DR   CDD; cd04486; YhcR_OBF_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR047971; ExeM-like.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   NCBIfam; NF033681; ExeM_NucH_DNase; 1.
DR   PANTHER; PTHR42834; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR   PANTHER; PTHR42834:SF1; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00932; LTD; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS51841; LTD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000246018};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..828
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015693656"
FT   DOMAIN          24..148
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   REGION          156..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   828 AA;  85622 MW;  4A1B7E0374A0EB58 CRC64;
     MRTSANARLI VAAAAFGLLA TGLAALPAQA NPAGTGLVIS EVYGGGGNSG ATLTHDFIEL
     YNPTDAAISV EGLTVEYFAA SGNPGDSHPL SGSVPAKGHY LIREAKGNGG TTALPTPDAT
     GSISMGGSAG SVRLSGAAGV IDVVGYGAAV VREGSPAPAL SNTTAATRDA ARRDTDDNAA
     DFTAASPAPH SSGVVTEPPP GPVSKTIAEI QGTGASSPLS GQQVSTRGVV TAAYPTGGFN
     GFYIQTPGPD TTPGASDGLF VFEPGFASSI AVGDSVEVVG LVKEFGGLTE VDATTVTEIA
     ALPAVVPNTE LPGSTCALPG TACPDTASLD AQREELEGEA FSPTAPMTVT DAYDFGVTSS
     RFFGEIGIAA GSTIPLVTPT EVVDAQDASG IAARTAYNDA HRVVLDDGSS ATYWNTSNTA
     DAQDEPLPWL TADHTVRVGA QVTFDKPVIL DYRFGWKLQP QRQVIGVPTG LVTFEQDRPA
     APAPVGGDLK LATFNVLNYF TTLGGDVPGC SAFVDRDGNP IATRSCSGAN GPRGAWNQVN
     FERQQAKIVR AINTMDADVV SLEELENSRV VDGGDRDEAI ASLVGALNAD AGNVRWAYVP
     SPSALPASED VIRTGFIYDP STIEVVGESK ILDVPAFDNA REPLAQVFKG TGGPAGQRFA
     VIANHFKSKA SGFDDGTGQG NANPDRVAQA RALVAFANSF AAERDTDKVF LTGDFNAYSE
     EDPVQEIEGA GYVALTSTDD PDEESYSFAG TSGSLDHIFA NPAARAMVTG VDVWETNANE
     SVFYQYSRYN YVGTDLYRPT VYAASDHNPE VIGINLRGRE TKPLHPRG
//