ID   A0A2T8HZ80_9RHOB        Unreviewed;       569 AA.
AC   A0A2T8HZ80;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:PVH30709.1};
GN   ORFNames=DDE20_04120 {ECO:0000313|EMBL:PVH30709.1};
OS   Pararhodobacter oceanensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Pararhodobacter.
OX   NCBI_TaxID=2172121 {ECO:0000313|EMBL:PVH30709.1, ECO:0000313|Proteomes:UP000245911};
RN   [1] {ECO:0000313|EMBL:PVH30709.1, ECO:0000313|Proteomes:UP000245911}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AM505 {ECO:0000313|EMBL:PVH30709.1,
RC   ECO:0000313|Proteomes:UP000245911};
RA   Wang X.-L., Du Z.-J.;
RT   "Pararhodobacter oceanense sp. nov., isolated from marine intertidal
RT   sediment.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVH30709.1}.
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DR   EMBL; QDKM01000001; PVH30709.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T8HZ80; -.
DR   OrthoDB; 3178130at2; -.
DR   Proteomes; UP000245911; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245911}.
FT   DOMAIN          7..550
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
FT   REGION          454..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  60847 MW;  B9F3A90AAB515FCF CRC64;
     MKTHEVDVLV VGSGAGGLAT AVAAAHRRLD VLVVEKEPVF GGTTARSGGW MWVPGNGPAM
     RAGVEDSAEK ARTYLQHEAG EHFDAERVDA FLEAGPKAVS FFEDNTNLQF DLGPFFADYH
     PDAPGGMDGG RSIVARPFDG RELGSEIRRL RPPLKEITFL GMMIGSGKEL LHFFNVMRSP
     VSAFYVGKLF MKFLYDMAFY GRPMRLMNGN ALVGRLAKSA FDKDVPIWTH APVSKLLRDD
     SGRVIGARVE RRDGPVEVIA RKGVVLAAGG FPQDALRRKE LMPHAPSGYE HVSPAPPGNT
     GDGLRLGESA GAVVDTTLPH AAAWVPISRP VRPDGTLGTF PHFVDRSKPG VIAVTRSGRR
     FVNEANSYHD FCQAMVARCR EEDGEGAEPA AWFITDHRAF RKYGLGFAKP APVPFKSLIK
     NGYLLQGKTL ADLAAQIGAD PAQLQQTVTE FNGPAARGED PAFGKGTTSY NRSLGDPEHG
     PNPCLAPLKD GPFYAVRLYV GDLGTFAGLK TNSNAQVLDE GGKPLGGLYS VGNDAASIMG
     GNYPGGGITL GPAITFGYIA ARHMSSAND
//