ID A0A2T9WNY6_9CREN Unreviewed; 341 AA.
AC A0A2T9WNY6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=RNA methyltransferase {ECO:0000313|EMBL:PVU69548.1};
GN ORFNames=DDW04_00185 {ECO:0000313|EMBL:PVU69548.1};
OS Sulfolobales archaeon SCGC AB-777_K09.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales.
OX NCBI_TaxID=2005260 {ECO:0000313|EMBL:PVU69548.1, ECO:0000313|Proteomes:UP000245662};
RN [1] {ECO:0000313|EMBL:PVU69548.1, ECO:0000313|Proteomes:UP000245662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC AB-777_K09 {ECO:0000313|EMBL:PVU69548.1};
RX PubMed=26341207; DOI=10.1128/AEM.01539-15;
RA Munson-McGee J.H., Field E.K., Bateson M., Rooney C., Stepanauskas R.,
RA Young M.J.;
RT "Nanoarchaeota, Their Sulfolobales Host, and Nanoarchaeota Virus
RT Distribution across Yellowstone National Park Hot Springs.";
RL Appl. Environ. Microbiol. 81:7860-7868(2015).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVU69548.1}.
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DR EMBL; QEFK01000001; PVU69548.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T9WNY6; -.
DR Proteomes; UP000245662; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR InterPro; IPR031341; Methyltr_RsmF_N.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR011023; Nop2p.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00446; nop2p; 1.
DR PANTHER; PTHR22807:SF30; 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR Pfam; PF17125; Methyltr_RsmF_N; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PVU69548.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245662};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PVU69548.1}.
FT DOMAIN 52..340
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
SQ SEQUENCE 341 AA; 38927 MW; 86EB39D2FB9B6D94 CRC64;
MESSIDEYIK KHADLFVHSP TARALKLAEK YKVLGYMAQR YLDFLKDEAE EFLRSCSLPL
RRAIRCNTLK LDSCERLVRS LELKGFKLEP VKWIKYFYWV NRAPSSPTLG STFEYLSGQY
YIQSPVSGVP VVELNPNPSD TVLDMAAAPG GKTSFIAQLM RNQGLIVAVE SSRDRTKSLM
SNLSRLGVAN TVILRQRVEK LVNVFFERFD RVLLDAPCSG EGLLPLDPAR RTKTSPEDLL
RFFETQLVLI DAAYKMVRPG GLLVYSTCSI APEENEFVVE YLLENYDDVK VENVSGSYPV
EEGLTEYRKY ILPEELRHCI RFYPHKSGTE GFFVCKLRRG N
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