ID A0A2T9Y919_9FUNG Unreviewed; 792 AA.
AC A0A2T9Y919;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=BRCA2 OB1 domain-containing protein {ECO:0000259|Pfam:PF09103};
GN ORFNames=BB559_005377 {ECO:0000313|EMBL:PVU88831.1};
OS Furculomyces boomerangus.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Harpellaceae; Furculomyces.
OX NCBI_TaxID=61424 {ECO:0000313|EMBL:PVU88831.1, ECO:0000313|Proteomes:UP000245699};
RN [1] {ECO:0000313|EMBL:PVU88831.1, ECO:0000313|Proteomes:UP000245699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUS-77-4 {ECO:0000313|EMBL:PVU88831.1,
RC ECO:0000313|Proteomes:UP000245699};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVU88831.1}.
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DR EMBL; MBFT01000593; PVU88831.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T9Y919; -.
DR STRING; 61424.A0A2T9Y919; -.
DR Proteomes; UP000245699; Unassembled WGS sequence.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 3.
DR InterPro; IPR015525; BRCA2.
DR InterPro; IPR036315; BRCA2_hlx_sf.
DR InterPro; IPR015187; BRCA2_OB_1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR11289:SF0; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN; 1.
DR PANTHER; PTHR11289; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; 1.
DR Pfam; PF09103; BRCA-2_OB1; 1.
DR SUPFAM; SSF81872; BRCA2 helical domain; 1.
DR SUPFAM; SSF81878; BRCA2 tower domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000245699}.
FT DOMAIN 225..338
FT /note="BRCA2 OB1"
FT /evidence="ECO:0000259|Pfam:PF09103"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 90267 MW; F48395806FBEE926 CRC64;
MVHSQGLRRP NIARGQSPGL FQSPLLSQKS KKTLFKPPTI SKPILSSSST QRSNTEELNH
NKKNDEITKL IPETSTVSNN TKENEIKASS ASSEVKKVSL KSFGKIYSIN ENIFLDKIPK
EVININFLNA KDFAFTNSPN GDGDSWGHKE AGLELRKNGY DFKKTGLSNH DSEKWIQTHY
QQLVWYLASM ARRFPENSQS FWSKKAVFER LVKIYKKELL ESHRPAIRRI LERDSSSKLL
MVLCISEVIS KNYILLSDGW YSIKAQIDNL LSRAVARKRL DIGTKIAIIG SQLKMGSGGF
EGISPLQIED PKSETAPYLL INSNSVRTAP WYQKLGFQPK NSKMSYSLHT LDPSGGSAFG
EIDIIVSRRY PLRYMETTTS NTRITRCESE ESRCQAEYDK MCRKKAQSLY SNLENESITN
RSALSTPDKL RSSINFDEKT GEELYSLFSN STDPSHLTSM LSTENQRKLE AYAESMKNER
AEIVNSELLD LMPPRKVVSF FQVLITDTQQ NKSVKSKPKY NRVVLSIWGS DHSVWSQFSE
GKRFKLYGVT PSGYKSEQTN NNSKLLNTNQ RNFLRLNVTR NTVWVPVKDN NFENLEGCDP
RKNLTISQLT QQNLRTDVDI VAIVESCVNA KNYGQDVTAI SLLPIELNDW GKYNIISNKP
QTKSNPFEKE SNIEDIQKSP ESEFGDELDH LANLYNLGGT QGTNSSTNTI FKEEKMIVTK
NRSSAKMNTQ EPKMFAYFSK QVFGTILLKP KEVIRIKDIY LGNWDQTRNV YFGTSRDYTE
YHTIKDHDNI NK
//
