ID A0A2T9YAT7_9FUNG Unreviewed; 649 AA.
AC A0A2T9YAT7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|Pfam:PF00264};
GN ORFNames=BB561_005343 {ECO:0000313|EMBL:PVU89456.1};
OS Smittium simulii.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133385 {ECO:0000313|EMBL:PVU89456.1, ECO:0000313|Proteomes:UP000245383};
RN [1] {ECO:0000313|EMBL:PVU89456.1, ECO:0000313|Proteomes:UP000245383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SWE-8-4 {ECO:0000313|EMBL:PVU89456.1,
RC ECO:0000313|Proteomes:UP000245383};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVU89456.1}.
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DR EMBL; MBFR01000313; PVU89456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T9YAT7; -.
DR STRING; 133385.A0A2T9YAT7; -.
DR Proteomes; UP000245383; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245383};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..649
FT /note="Tyrosinase copper-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015761584"
FT DOMAIN 65..231
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|Pfam:PF00264"
SQ SEQUENCE 649 AA; 73164 MW; 90E35DCA2C3BA6D8 CRC64;
MIINISKYTS VILAIFYLEA LLGVSGQLEK CSGKIDVRKE IRKLSTAEMK VMISATTQMY
NAGWYDWFAY VHVQISSSIH GNAVFLPWHR AYIREVELTA KDYEPTFSLP YWDASIDYSN
PAKSIVFSDN YFGGNGVGSK GCVKSGLVNN WTVEIPNKHC LRRKFNDGKN ISPWESPETI
TSMLQTTKND YNLFRQKLEF GIHASIHNGV GGDLSSMNSP ADPIFFLNHA NYPVKVNDVM
KLGYGDMCYE YDDLPIVKKR DNKNEPTLSS TPVKRMSSNL TDRKLILGKR KEDSVEPIPA
KAEKQANIIV DNKSIQNVTN VPQMSIVAVL DGPALDKFFP LISKNELSSN SIALPSVVTA
KAGEFAKEYL NNVTVAETKP VDVPIESKSI TDALIKTTEK TSKNPDFHKK KSRKKKNDIP
SKFKVMVIKA IIQAVATYGG KLFGMSATRC KPIQQVVDAA TRTLAKSRTR AFGKWSGLRT
WISDLIKQKK NDKSHISKWI AATEAVYPEL KTHINYVFKI RNGTYWAARR YAKSGFIEKR
FIEECPFCRN IAPETIEHML LESQVASKPT LFSASISMRL VGKLLEEYLK LSSTRICKDP
TVLFVKTTLA TANFLNLIVR LSYLILNNIK LLQIPKINSN RLRLLYRDS
//
