ID A0A2T9YDC1_9FUNG Unreviewed; 908 AA.
AC A0A2T9YDC1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=BB559_004694 {ECO:0000313|EMBL:PVU90305.1};
OS Furculomyces boomerangus.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Harpellaceae; Furculomyces.
OX NCBI_TaxID=61424 {ECO:0000313|EMBL:PVU90305.1, ECO:0000313|Proteomes:UP000245699};
RN [1] {ECO:0000313|EMBL:PVU90305.1, ECO:0000313|Proteomes:UP000245699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUS-77-4 {ECO:0000313|EMBL:PVU90305.1,
RC ECO:0000313|Proteomes:UP000245699};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVU90305.1}.
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DR EMBL; MBFT01000490; PVU90305.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T9YDC1; -.
DR STRING; 61424.A0A2T9YDC1; -.
DR Proteomes; UP000245699; Unassembled WGS sequence.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR002975; Fungi_Gprotein_alpha.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF355; GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR Pfam; PF00856; SET; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR01241; GPROTEINAFNG.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245699};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT DOMAIN 765..893
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 373..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 908 AA; 104232 MW; 91FAD97531EAA16D CRC64;
MGCSSSKDDF EGKRVNDEIE TQLKKDKANL RNEVKMLLLG AGESGKSTII KQMKLIHGNG
YTLEEKESYK EIIFSNTIQS IRVLLEAMEN MEIPLDNPGN EKYVNLILDY PPQIEADVFP
SDSAEAVKML WHDKGVQECF SRSNEFQLND SAKYYFDSID RLSQPGYIPT DQDVLRSRVK
TTGINETVFN VGELTYRMLD VGGQRSERKK WIHCFENVTA ILFLVAISEY DQVLIEDETV
NRMQEALTLF DSICNSRWFA KTSIILFLNK MDLFKAKLPK SPLKDYFPGY TGENDVDSAG
EYILRRFVSL NQSDTKQIYT HFTCATDTNQ IKFALYNPNT KEKAISPYHL VKNMVFLVAI
NLISLNKCLE SMSQPKNSDN KEETKSENNE LQVDSDNGFV GYVEPGKSPN NKDSIQKSNP
ISQKKIDEPI KRNFLKIRLF YKERDPGLIS HRNNIPITRH RKQNVYVEIN RNKNPGLSNP
KHDQNTNNPT NANEVSYLRK RKAIEKVQRP RWYNQTYILF LALRQCKNYT ASRKDLLEKA
VKLDKKMSKE LGIPKVYTGK TPLNSASAIL TRNMDLLFIQ KKPENSKHFV FTLAYKPGDF
QSALENYNSW MKTLVEVDWP KCFGQDEYKQ VSSYETQMTD IITEKHEQAP DQSEKSIESI
NTDHAQHTID NPTDSSVMDL YKSKNEHDTP ENENNSQNKQ NEENEPNTKK TSISGCNHLE
AESYDNMSEL SLNSNLDSPK TNNVNIDTPF TDEKTDIDIP KKWEDIVEVR KSTIPNAGDG
LFAKRFLPAG IPLGFYFGVP MTEDEFDSLK DRVGLASSYS IMYRKTVLDG TDENGMPYTD
LNGPVFCPFH FMNDDREDLN SNVTFVEGRF VNQVIVFTIR NIMPNEELFV YYGSEVDRGS
WGKDETTK
//
