ID   A0A2T9YL96_9FUNG        Unreviewed;       412 AA.
AC   A0A2T9YL96;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE            EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
GN   ORFNames=BB561_003459 {ECO:0000313|EMBL:PVU93116.1};
OS   Smittium simulii.
OC   Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC   Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX   NCBI_TaxID=133385 {ECO:0000313|EMBL:PVU93116.1, ECO:0000313|Proteomes:UP000245383};
RN   [1] {ECO:0000313|EMBL:PVU93116.1, ECO:0000313|Proteomes:UP000245383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SWE-8-4 {ECO:0000313|EMBL:PVU93116.1,
RC   ECO:0000313|Proteomes:UP000245383};
RX   PubMed=29764946;
RA   Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT   "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT   Symbiosis.";
RL   MBio 9:e00636-e00618(2018).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC         glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC         ChEBI:CHEBI:83408; EC=3.1.4.46;
CC         Evidence={ECO:0000256|ARBA:ARBA00029315};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVU93116.1}.
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DR   EMBL; MBFR01000138; PVU93116.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T9YL96; -.
DR   STRING; 133385.A0A2T9YL96; -.
DR   Proteomes; UP000245383; Unassembled WGS sequence.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR   PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR   Pfam; PF03009; GDPD; 2.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245383};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..412
FT                   /note="glycerophosphodiester phosphodiesterase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015508561"
FT   DOMAIN          32..400
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
SQ   SEQUENCE   412 AA;  47345 MW;  B7019C630794DAFB CRC64;
     MFKSILTLTS LALLATSTYS RSVWNTLDGN PSKLAGHRGE KAFMPEHSLG SYHMAALMAV
     DYIEPDLVLS KDGVLMVVHN EWLGDTTNVA NLTQFADRKK QYTFKGKYSA INRTEWFVWD
     FTYAELKTIN RVQDTGYPYR PQYFNKDFSV LSFTEYLDHV EGLIKTLDRP FGVIPELKSP
     EVFNALFPSA NGRGYEDRLL DIMTKRNYTL NQPPPLSPVM QSGDLLDNIL NIKPKNYAKP
     NYKLAALQSF DPETCEYLGK KTKIPIVSLD QNKPWMYTPK GLDKIASYSK ILSPGKDLLL
     AGPALYFEYN KISYNKTEIE SMGGFLQPKD LVREAHKRQI EVSPYTLPDS RQPSGLLCTR
     YNDTRFEYCP KNRKEEMFYF FDLGCDYIFV ENIFEAQVLR LAFDNKIDSE DC
//