ID   A0A2T9YZM9_9FUNG        Unreviewed;      1699 AA.
AC   A0A2T9YZM9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Ras-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BB559_001906 {ECO:0000313|EMBL:PVU97801.1};
OS   Furculomyces boomerangus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC   Harpellomycetes; Harpellales; Harpellaceae; Furculomyces.
OX   NCBI_TaxID=61424 {ECO:0000313|EMBL:PVU97801.1, ECO:0000313|Proteomes:UP000245699};
RN   [1] {ECO:0000313|EMBL:PVU97801.1, ECO:0000313|Proteomes:UP000245699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AUS-77-4 {ECO:0000313|EMBL:PVU97801.1,
RC   ECO:0000313|Proteomes:UP000245699};
RX   PubMed=29764946;
RA   Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT   "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT   Symbiosis.";
RL   MBio 9:e00636-e00618(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVU97801.1}.
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DR   EMBL; MBFT01000098; PVU97801.1; -; Genomic_DNA.
DR   STRING; 61424.A0A2T9YZM9; -.
DR   Proteomes; UP000245699; Unassembled WGS sequence.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd21206; CH_IQGAP; 1.
DR   Gene3D; 1.20.5.190; -; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR000593; RasGAP_C.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR   PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF00612; IQ; 2.
DR   Pfam; PF00616; RasGAP; 1.
DR   Pfam; PF03836; RasGAP_C; 1.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00015; IQ; 5.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF143885; RGC domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS50096; IQ; 5.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245699}.
FT   DOMAIN          166..284
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          848..1063
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          334..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1699 AA;  193808 MW;  C66DAA84BFB81AF0 CRC64;
     MVRVKPTSIP DSNTLTSEAD IKNTSQNFNI KASLKSPIDA SLSNDTIQIL NSSTNSLKSL
     SVNKNQTQKT FSSHVNPHPY PLYSTDILSL SNAQILSSLS KNGQDIPIRP FSSLLLEPPD
     SPDVAGMKGR HKLQKDSDIS SADPLLIRNG KWCDIKRKYL AAYEYLCHVA EAKEWMESCL
     GYELRPIEEL EESLRDGVDL ANLAKTFCPE AVGRIYSGRR SSRFKSRRKS KKLNFKHTDN
     INYFQNALKK IGLPKLFYFE LTDLYNAKNI PRVIYCIHSL SHFLESLGIT VGIKDLVGVL
     EFTPEQLEQT QLKLNNLGPT NMVQFKGLNR RISSQSDSAN INSTTPAQTT DSNSDANSDS
     GASTLNSKGS KSLQKIETRS VQSLEFVDDI PTDITRYWEQ NIDTLIKIQL AAKRYLAVRD
     VIEKRQIKYY LEVVHSTKLI QTLIRGYFAR KFYKTLQEKN KQIQPKETFI SNSSASSTFN
     PDTDNQEDEV VSILSENIVT NDEKPSLEKE VFLNEPESQD KNDEIEFEKK VIIVQALIRG
     YLARKLFSDM DAWTTLIKKI QAHCRGFLTR SEFKDKLAHW KKVNQDIKVV QALARGKLVR
     NKFKSNDKHY ERNIKVIVKM QNILKAKIAR RAYRTLTIED SIPTPKIVRS CAPLLEETDQ
     DLAEELELEK LRQKVVRQIR DNQHTEQSLK GLDIKIALLV RNKVSLEEVI KHTKSFLSFF
     SEIRNPSFIN NPAFRSNVSN FSMSGAAPPG SLYSLRNLSR DSRRRLESYQ HLLYLLQTQP
     LYLSRLLLHQ KEQFNTNGYT TSTNNFAGNY QGTTTRLVEN KGVSTSNKNE ILSDSTIMAM
     FGYSQNSREE FLFLKLIQAI MDMEVDKMDS LLDSMDTEFI FLRLSNLHNK GDEETTYLCN
     TFKPVLLKMF ENTSLDLESD PLVIYRTFIR ENEAKTGMKS NKPYNISRDD ALNDPEVRPI
     FIQRLLQLRL LADEFLNAIM STLDTLPYAI RFLARELKSL LITKFPNVHE KNILKVVGST
     IYLNYFNHAI VSPDKHGVVD TPINTLQRSN LSQVSKILTQ VASGTAFSDD DLFLQPLNNY
     VNFTAAKFTE YNYSLASVAS LETHFHIDEF TDLVSIHKPT LYLTIEDIMN IHNTILQNIK
     IIAPSTSESQ EVFSGEEALK SWLRRTARKS GLRKYSSMYF GESDAVLPLK SIASMSNLNE
     NLEELVDVLP PGTVLVEKND DTNRDNHVLV LDDPLNVILR ELGNPPRIHR DPYARSMIML
     NLADRFADDS MAFLSNTQGA NQLSLVSNSS KLINSSLMNI GLNEYDEKSL GDSSSLHTLF
     LTTKRIWVAI LRVKSGSSLL DILNSPSTAE DEARWRYVVE DENTKLDERK KRQQELWSSQ
     QRAQQLLQST IQTLGFSSSP KEALRQIPDI PKSVPPIPGE ETISSWKKLS FEQIKSIVRS
     SMNVLEKNRF TERPRRSGIG ATNRKNSTRN SIGFNSGFKI RSSDKYQGML NAIVKDLKNK
     NGRREQRHAE LRRVRQNLVS LGIKTQYLDS QREFYEKYLD SCIQQLTLSN NQKTSGQTLG
     KRLSRTGSFI MKSIKSKLPL SKNIFNEKTN VESKQNSKFG QYKYNAEKLY LKGVLVSVEG
     YSPRQLDKVG FSISCDEPGV FEIGITYMGS EIVYETSQIK LEDLLQKQYD NQTIFTLFND
     TVKFNVNLLV YLINKKFFI
//