ID   A0A2T9Z8S2_9FUNG        Unreviewed;       983 AA.
AC   A0A2T9Z8S2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Spindle assembly checkpoint component MAD1 {ECO:0000256|ARBA:ARBA00022019};
GN   ORFNames=BB560_004597 {ECO:0000313|EMBL:PVV01001.1};
OS   Smittium megazygosporum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC   Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX   NCBI_TaxID=133381 {ECO:0000313|EMBL:PVV01001.1, ECO:0000313|Proteomes:UP000245609};
RN   [1] {ECO:0000313|EMBL:PVV01001.1, ECO:0000313|Proteomes:UP000245609}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-DP-2 {ECO:0000313|EMBL:PVV01001.1,
RC   ECO:0000313|Proteomes:UP000245609};
RX   PubMed=29764946;
RA   Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT   "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT   Symbiosis.";
RL   MBio 9:e00636-e00618(2018).
CC   -!- SIMILARITY: Belongs to the MAD1 family.
CC       {ECO:0000256|ARBA:ARBA00008029}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVV01001.1}.
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DR   EMBL; MBFS01001457; PVV01001.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T9Z8S2; -.
DR   STRING; 133381.A0A2T9Z8S2; -.
DR   Proteomes; UP000245609; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.30.457.60; -; 1.
DR   InterPro; IPR008672; Mad1.
DR   PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR   PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR   Pfam; PF05557; MAD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245609}.
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          435..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          822..847
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          235..262
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          293..338
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          403..430
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          534..561
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          606..668
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          747..802
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        18..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        828..847
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   983 AA;  110304 MW;  05574C63BDB8BB15 CRC64;
     MEQNPSNFNA HPEDLVKKTP LPSVRRNRLA RELESARKDL PTPSFPHLSQ MPPPSTILRN
     RFREFLNGPT IPSTNQKKRR ILDSKANLLP PTPLQQNVSD FTPSSNRISV LNQIDPPTTI
     NESFVSKLKN VYETPVNSKV SEPVQLSNSF FSDSPNPMSS KDLALESSSP SNFNYFVNSE
     SPNSGSLFST PKNLSKQLSP YSESDTGPVS RPASALKKIF MQIQSDSVSN LSFEQNANNL
     EKAQYEQKKS QLEQNKLKIE IEKLTLDYSS KLESQAKKIA SLEKDLKYQI IKEKEFTDNI
     DSLKSQLDQS NQKNSEIIKN LEHLLENESK LRADQERISE VSISSLKSKL STFESRVSKL
     DKYTNLMNKQ LLSILAENDP AIAKSNLDEY DLQMTISCIK STLSSKNSTI QSLKNDVSDL
     RNTLDTQLSD IPSAEESLVS VSDSNPDITQ TNNSQQPLSN ENQSHPSLNR ALASSVHTIN
     KLKSQVASLD KIIANNVSLL NASRSENSLL LNQIESLKLS VKNTPAFEQK NRSLEEKLSH
     FESLQSKYSD LEARYNDLLE KQNEWNSLMD FKDIKPNPFE NSLLSPSSSS ALYKLKSELS
     LSSSRIKELE SLNQSLLSQI SKYENDKLLN EQNISSLNSK MKAFAFDLAN SQNALDLANK
     EIKILQGHLK SYDSEESNLS ENTVNSAKSE RINQLEEILT LQKSQISELQ NLLSNTCLQT
     SLPSNDKIIS KANQINSEND ESFQKFINIL LTDKNELTEK LSSATETINS MKAENEQLAS
     QIKAYERNLS QLESQLARME FVVGSGDYNP LTTRLKELLE NKSDEDMGQN IENSSASNSN
     QDASANPAPK SALFLTIENL QIENENLVKK LDDSNKVIKR LKGVWKTKAS ELREAVYTLL
     GYRMDFLENG RIRLTSTYTK NQNNSFIFAS SSEEKGATEL IGGGNKEFIN SLKSQIRYWI
     VDRGSIPGFL AAVTIQLLDE ESP
//