ID A0A2T9ZBI4_9FUNG Unreviewed; 1390 AA.
AC A0A2T9ZBI4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
GN ORFNames=BB560_003635 {ECO:0000313|EMBL:PVV01925.1};
OS Smittium megazygosporum.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133381 {ECO:0000313|EMBL:PVV01925.1, ECO:0000313|Proteomes:UP000245609};
RN [1] {ECO:0000313|EMBL:PVV01925.1, ECO:0000313|Proteomes:UP000245609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-DP-2 {ECO:0000313|EMBL:PVV01925.1,
RC ECO:0000313|Proteomes:UP000245609};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVV01925.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MBFS01000698; PVV01925.1; -; Genomic_DNA.
DR STRING; 133381.A0A2T9ZBI4; -.
DR Proteomes; UP000245609; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245609};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..235
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 288..329
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 583..645
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 783..810
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 840..895
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 962..1016
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1390 AA; 159233 MW; 9D4F8BB8A5BA9D3D CRC64;
MSVIEKLLIR GIRSFDPEEP SVIEFYSPLT LIVGRNGSGK TTIIECLKYA TTGELPPNSK
GGAFVHDPKL AGETAVKAQV KLKFKNINNK DMVCTRSLQV TQKKTTVSMQ TLEGVLYIAP
NKETGQEKIS ISTKCAELDV EMPLQLGISK AILENVIFCH QEDSNWPLSE PVALKKRFDD
IFSATRYTKA VDALKKLRKD QAVDFKILSN DLKHLEENKR KSDKIKREIS GLLTKSDEIA
EEIKTLQADE KSFQDTIDEF STTTREFLDT DAEMLKTLHE KNITEKNLNE TTEHLEILDL
SIDELEKIIS EQETEKNNLQ KTIDNLNSKI SMKVSKVNEL QTSINENQIN MGKYEILQNT
FNNNVKRRSD ICSLIYSENR EQIILFNSQD KLDASSENLD FENKCLAETI YNYVKTQYEY
FTNLAMQDNG KLNRIENEFL SEKNDFNILN AEKRQLLNQL DIQKGQKHNE IAKLEGLIQD
QGTLQAELLS LKNSLGTEKI YLADSIIERE KLDFATKSNS IKSELELIDE EVVDISCDSA
RAQSSSELIG KSELILDSIN AKTKSLDTLI TKLGKYVLDD PKNADFKDMR DDIKNQIKDL
DANISSTSSI CRDLDIELAS KKDKLASMKD NLTQFNSELA DLERDLIVSV TGNEYEAEIS
SVQKNVEKVS ELIAKNKSIT VLYKSFFDEV MFKQSCPLCF RSWDNPDDKE KFTESLKTKI
MNVPSSVQDS ETELVSLQGS LNKLKSIQPS IYRARNLRDC IIPELVSSIS DLSQDILTLS
SKTAEKSAEN KDLENKKADL SETLKLLEEI INLSASLKTE KDEYNKITIK INTEGSTKSS
ADYAELLNNL QKKSRELRTQ LDLNSQKTLE IQKKISKHEN NISQYQNQIQ RIEQKISLNS
SYLQKKNDLF EETKEIKKRV VDILNSIEIE EKSFESKESE YLNSKKSVQL DIDLNSSKSN
EMKSHLDNLS SLNNDIAKSE EEMDIQALFA STKANIDELK SQIHTINGEI DILRVKLSDN
EIWKNNYEQK VRKVHDNIKV KKLQDEILSL DQTIEKINLK KVEMNDAILG MIKLYRDQKY
ISFQDSNKRV KKSEADDFDT TLRRYCEIEE LFMDSKTKNE LVEAESLSKK RGFSNIDKSY
GNENFKFTVT LELINLIKSK LRSYLDSLAT TKASLIGEKK QIETQIQHFK NDIKANYKDI
DSLYIEKMIA YKSLELAQED LEKYSKGLDN AIMMYHSMKM QEINKIIREL WVNTYMADDI
DTIEIRSESE KTKLNRSYNY RVVMIKGGQV IDMRGRCSAG QKLLAALIIR LALAETFAMN
CGILALDEPT TNLDEANIES LARSLSRIIA SRQYKSKFQF VIITHDEEFL NMLGKSDLTD
YYWKVYKNQK
//
