ID A0A2T9ZKX6_9FUNG Unreviewed; 2182 AA.
AC A0A2T9ZKX6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 08-NOV-2023, entry version 18.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN ORFNames=BB560_000209 {ECO:0000313|EMBL:PVV05266.1};
OS Smittium megazygosporum.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133381 {ECO:0000313|EMBL:PVV05266.1, ECO:0000313|Proteomes:UP000245609};
RN [1] {ECO:0000313|EMBL:PVV05266.1, ECO:0000313|Proteomes:UP000245609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-DP-2 {ECO:0000313|EMBL:PVV05266.1,
RC ECO:0000313|Proteomes:UP000245609};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVV05266.1}.
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DR EMBL; MBFS01000020; PVV05266.1; -; Genomic_DNA.
DR STRING; 133381.A0A2T9ZKX6; -.
DR Proteomes; UP000245609; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR PANTHER; PTHR10063:SF11; RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED; 1.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000245609}.
FT DOMAIN 1803..2017
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 776..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1656..1685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2048..2077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1665..1685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2048..2062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2063..2077
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2182 AA; 248800 MW; 98843A2F6EEDF995 CRC64;
MSFITSNSKN QTEILPEASI RFVFLSDDIE FMDLADSCCN LNKLPPNSLK YPSEDFLLTL
TELNKGKKSA PHNWLSVKGR TSSKFSHLLS YLKSLADNEL IFIFVKYHEK IFELGYKMIL
KVAQKVKDPQ LLTTTDLFVK FMNAVDLLEK FFYLIPIKLS QGWKQNEFVS VLSLILDHGN
NSHFRIYGFR LLLLYINSLL GKIPESVCNL FKNSIIIQSF IEEDLFRKDS TVENIINSLH
LTPNSSMFDF GQISIQSNLL PNKSIYPIEK FDSPFYMSTQ SVIATRMIQE FFYNTLYISH
FVVDDSPLSD TSISYGYLTG KYSNFVHVPS KDAFRFQAYP NKHDDTQSIY DNLSVYLITP
EDAENSLSSI LGLGGVPIPL MRMMASFLLK YVSFIGKELN YISDFSGSPV LNDKLNIMTF
IPTQANDFEY PEKLRKYQQH IWFESNKSLS IFSESVVFGI LKLDKATITS SGYNPMVAEC
IYQDIMDTQM ATLNIFRSFL LMDVSRRPAQ FVKPIEDTHL AKWSSLMLKY LSSIFFSMSS
NVAIQEPWTF SRFSAFYLSV TIFRTLFKMS DNEIPLNIKD ASLSHLFEIL ESMLIKPVLK
GEDPSDPYCL GSQAIMILFE CIVEGWLITF DNKPKYWVKF EKIFFIESPW NTRYHVWANV
LQSLTMTLGT RFYNIDHLEL LQDYLFSGQR TKGGSRGLKK KFETIQKNIY ISIRNGDEVT
VPFSSYNPFI VTSKCSLISS QIVLDYLWKK KELREKDFNY VLNTIKSNQL SSFSETKENA
PVNMEESRSN LSEFSETNDV PSKEENVYSS NLKYNLDSCI SVNSLARYKN SALDVNLPNV
VQDSYNATSP LPLSKNISPN VQKKHITLPH GKHLTGPNQF QIPGIEPNTS GNDPEGSNFG
DVPEKNKLFR TSTIENRYSA SYLKNEYDAV METQKMKNPN ILHSSNTAKS LSLTPSGYKF
LSQSPGLMIK NRIKSSNLHK RSASVFGSIV NKFKINRKKL ESSGGNLLND ESSSEKETII
QLERLLNLND DHLNEWILVR TPFFDTFNLD SDLNWDLIFK HIKINVVWSK WWQLVERPMI
IRDLGAKKIV TTGLSRAWDI YLILTDRQTA TGVSFIKDEK LAFAHWLFEL CRGPQDSDEC
SILAMRAISR VFCRTFSPNY SIPSMYQALF YRIVLESLSE KALEFEYGVQ LLEVTLIECK
RMFALDVPGC LMVVKSLTGT LLRIFSPDFS YSLSDEAIFG ATILLISSIT LLHSSPQETF
EKNKITPTVT FTSSSDSVVA WEPFDRKKTL DQLCYLLLKL AGEHSLILKN VSDNNQTRIV
CKLIGTLSVI ILMNNTPDKI TENAINLIIS FLFSPNKQYV FVALDSLRAL LASNEQQKIL
DLLGHKLAFL ITKFLVYCCY EQLDRYVDTS DSHYIRVFGD SLYLLMSYIT LVPSIISGRN
FDVDSSERMD LEVFLFKDLL QDRINELYSK PKPLALHKYN YAISMTVMSS KSGYHSPHDI
LTELEKLPFI LSPEYKSRMK DYSPENAPEL NSIKQLMLAY SFSLIQNYKT YNPKHEFIKY
LNDSSIISNE LDGIANGDEM MFFGYGTSII SVIKPKLSSE LKITTRSVTG KHAGYFRSDL
VDLILSDNMD VVPQAGLEKE ISNFLKSNPE FNLKNLVPSN KVESEKGDSS TEDTDSEEHS
ISSHGDDLEL EFPKVRFISS YDADWVSYKA SAANEFCSEN EKIERLVSNT KKFVFSYKSK
EEIALLNVSK GDPKVFSKSE KREKSIFQEL RLFLQHFGFF DWTSSNPKLF KLLLPSNNLF
KELSLLDRLT PKECIKVAIC YVAPNQTTES EILSNDKESA SLAFREFVQS LGYPVTLKNF
GGYTGKLSTD GSDGETAPIY VTHNTVLVFH DATEMPTDKN DPKQLKKKRH IGNDFVHIIW
NENFCDYRPE TITGDFGNAQ IHIRPLLSNL GSYGISLYAD QRIDAIGPLV DNMIVGPELL
SDIVRSWAIC ANRQSLWMRS PVFYSPLLVR MDSINQIISK NLFPEWSEKT YSGSFLINPG
VVAKLSSDEN QHSSNIGDSA TSKKVDNKVK TDTDKRAEKI RNDQTIEQPE IEISDISMGL
SNINMLNDGE KTRTHTLEYD EKAAAAPNKP PVEKEQVTLS VSETTQDVNL KTLKPKPNLG
YFNKSEDDIF VTRILSQQST EH
//
