ID A0A2T9ZLH5_9FUNG Unreviewed; 872 AA.
AC A0A2T9ZLH5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BB560_000110 {ECO:0000313|EMBL:PVV05387.1};
OS Smittium megazygosporum.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Smittium.
OX NCBI_TaxID=133381 {ECO:0000313|EMBL:PVV05387.1, ECO:0000313|Proteomes:UP000245609};
RN [1] {ECO:0000313|EMBL:PVV05387.1, ECO:0000313|Proteomes:UP000245609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-DP-2 {ECO:0000313|EMBL:PVV05387.1,
RC ECO:0000313|Proteomes:UP000245609};
RX PubMed=29764946;
RA Wang Y., Stata M., Wang W., Stajich J.E., White M.M., Moncalvo J.M.;
RT "Comparative Genomics Reveals the Core Gene Toolbox for the Fungus-Insect
RT Symbiosis.";
RL MBio 9:e00636-e00618(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVV05387.1}.
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DR EMBL; MBFS01000010; PVV05387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T9ZLH5; -.
DR STRING; 133381.A0A2T9ZLH5; -.
DR Proteomes; UP000245609; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR CDD; cd20264; Complex1_LYR_LYRM4; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd02340; ZZ_NBR1_like; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR045297; Complex1_LYR_LYRM4.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR15090; SEQUESTOSOME 1-RELATED; 1.
DR PANTHER; PTHR15090:SF0; SEQUESTOSOME-1; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245609};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 270..321
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 439..474
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 40..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 98741 MW; 4D87D57101D7368D CRC64;
MEMENFQLNS KLSLLTMGAV VGFVSCIAFM KIQEALKVST RSAKYRRPGS SGRNRGNRNQ
TRSLLRRVNA LRRIPSNELR ERLENEDSSQ AQDSLNQMQN RLLDLLALNP EQFSNEEILS
DITSEIERQI NQFENSFNQS LAENELQGLN HDSIFSLETH GINDFQEQVQ ESQNNEENNL
QLEASQDDSL AVPNHDAADD QTEDDSNTEI QESSMSQLYQ NGNMSFEYPD PEILEKYKNI
LSGAGGSKFK LFQLLYLLYD VKEKRKSLVH SGVACDQCQE SPIKGVRYKC TQCPNFDLCE
FCESRNVHSE HVFLKIKIPT STLFLQHTPI LNSFYIGNML GDIMPAGFAQ HLISEAMKMK
PKFSQSELYG LYDQYCSIAT YDRAKHGIGI TSFAKCMGIQ GVRGPFLNKI LFEFYDSNDD
SLIDFNDFVY GMGIMHRGSL EEKAREAFRV YDQDDDGYLG LEEFSQVIYA YFSYSQKLTQ
DISFCSNDDK ILSIDEVLKD QPISAAFTGI IPSDSQSILN KNMERMREEI SLIRQPDVRQ
EIQENLYRNS TLARSALSNL SGAVHTDGSS DAQMSGASSS LDEFTNAVQS ADSSRSRFSI
SVDGADLKNP KKDTTSGSDS ISLKPKDNTK LGSKKVANEG QSIIGESSKQ YKEGQNLPDS
IDIHIEKDST ISTFTDKEEA KDTYATSSEG ISDKTKSTDL DPALDLNLNM KDALVWENSI
LDHHRKKNGY IESLENSVIA SARNNIWEDP SLQEDWPILD VMLMESVSIL ASDLFELIPS
RSRKYGLSEE EFVELEGKVL YERLMVAAKN FKTYNFRAYF ERRISQDYKA FGQAEFIQRY
KSQLPVLERQ SAINSMYSFQ SSIMDTQNEE AA
//
