ID A0A2U0S1N3_9ARCH Unreviewed; 361 AA.
AC A0A2U0S1N3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=tyrosine--tRNA ligase {ECO:0000256|ARBA:ARBA00013160};
DE EC=6.1.1.1 {ECO:0000256|ARBA:ARBA00013160};
DE AltName: Full=Tyrosyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00033323};
GN ORFNames=CW691_05050 {ECO:0000313|EMBL:PVX25297.1};
OS Candidatus Bathyarchaeota archaeon.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=2026714 {ECO:0000313|EMBL:PVX25297.1, ECO:0000313|Proteomes:UP000246112};
RN [1] {ECO:0000313|EMBL:PVX25297.1, ECO:0000313|Proteomes:UP000246112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bin-L-1 {ECO:0000313|EMBL:PVX25297.1};
RA Yu T., Wu W., Liang W., Lever M., Hinrichs K.-U., Wang F.;
RT "Growth of sedimentary Bathyarchaeota on lignin as an energy source.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-
CC tyrosyl-tRNA(Tyr); Xref=Rhea:RHEA:10220, Rhea:RHEA-COMP:9706,
CC Rhea:RHEA-COMP:9707, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58315, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78536, ChEBI:CHEBI:456215; EC=6.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000069};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|RuleBase:RU363036}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVX25297.1}.
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DR EMBL; PIXT01000101; PVX25297.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U0S1N3; -.
DR Proteomes; UP000246112; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004831; F:tyrosine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR002305; aa-tRNA-synth_Ic.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR023617; Tyr-tRNA-ligase_arc/euk-type.
DR PANTHER; PTHR46264:SF4; TYROSINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR46264; TYROSINE-TRNA LIGASE; 1.
DR Pfam; PF00579; tRNA-synt_1b; 1.
DR PIRSF; PIRSF006588; TyrRS_arch_euk; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363036};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363036};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363036};
KW Reference proteome {ECO:0000313|Proteomes:UP000246112}.
SQ SEQUENCE 361 AA; 40990 MW; 9B4401EBB99A3ED8 CRC64;
MDLQKRIDLV MRNTAEVVTP QDVRTLLETN NTPSAYWGFE CSGLLHIGIG LVCSAKIKHL
VNAGFKFTIF LADWHSWINN KLGGDMQNIR TCGEYLKQIF VALGLTPDKV EFRWASEITD
NVEYWEKVVR IAKSVSVKRT WRALPVMGRE TSMTDIETAW VFYPCMQAAD IFEMNMDVAC
SGIDQRKAHM LARDAAEKLK WTKPICIHTP LLIGLQGPQS AEKMFDENAE LNVEISSKMS
KSIPQSSILV HDSAKDIASK IKNAYCPPKI VKNNPVLELA RLIVYPETDR LVIPRPDKYG
GPETFESFET LATVYREGKI HPLDLKNGVT DSLTEILKPV REHFSRHPQT LEKMLKIEIT
R
//
