ID   A0A2U0SCH2_9SPHN        Unreviewed;       398 AA.
AC   A0A2U0SCH2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=4-hydroxytetrahydrobiopterin dehydratase {ECO:0000313|EMBL:PVX29073.1};
GN   ORFNames=DD559_06775 {ECO:0000313|EMBL:PVX29073.1};
OS   Sphingomonas pokkalii.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=2175090 {ECO:0000313|EMBL:PVX29073.1, ECO:0000313|Proteomes:UP000245890};
RN   [1] {ECO:0000313|EMBL:PVX29073.1, ECO:0000313|Proteomes:UP000245890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L3B27 {ECO:0000313|EMBL:PVX29073.1,
RC   ECO:0000313|Proteomes:UP000245890};
RA   Menon R., Kumari S., Rameshkumar N.;
RT   "Description of Sphingomonas pokkalii sp nov, isolated from the rhizosphere
RT   of saline tolerant pokkali rice and its draft genome analysis.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVX29073.1}.
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DR   EMBL; QENQ01000001; PVX29073.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U0SCH2; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000245890; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          253..369
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   398 AA;  44054 MW;  8FF79313910FB3D0 CRC64;
     MTVLSGFLGA GKTTLLNHIL ANREGKRVAV IVNDMSEVNI DADLVRGGEA ALSRSEEALV
     EMTNGCICCT LRDDLLQEVR TLAEAGRFDY LVIESTGISE PLPVAATFSF RDEAGKSLGD
     VARLDTMVTV VDALNLLADF DSEDFLADRG ESLGEEDTRS LVGLLVEQIE FADVVIVNKA
     SDVSPVQLAR VRQLVASLNA DARIVTADRA RVGLDMVLGT GRFDEEAAAR NPLWAKELYG
     YASHRPESEE YGIESFVYRA RRPFDPARFY RFLTEGGLAR VVRAKGHFWL ATRPDWVGEL
     AVAGRQTMTA RLGRWWASVP KHHWPDDGRF EEFVVAHWDG DWGDRRQELV FIGIDMDQAA
     ITQALDACLI AADHFDPRAW TRLVDPFPAW TAEQAALA
//