ID A0A2U1AJZ2_9BACT Unreviewed; 207 AA.
AC A0A2U1AJZ2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:PVY36705.1};
DE SubName: Full=Cobalamin-binding protein {ECO:0000313|EMBL:NMD86102.1};
GN ORFNames=C8D82_13331 {ECO:0000313|EMBL:PVY36705.1}, HF882_05840
GN {ECO:0000313|EMBL:NMD86102.1};
OS Victivallis vadensis.
OC Bacteria; Lentisphaerota; Lentisphaeria; Victivallales; Victivallaceae;
OC Victivallis.
OX NCBI_TaxID=172901 {ECO:0000313|EMBL:PVY36705.1, ECO:0000313|Proteomes:UP000245959};
RN [1] {ECO:0000313|EMBL:PVY36705.1, ECO:0000313|Proteomes:UP000245959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14823 {ECO:0000313|EMBL:PVY36705.1,
RC ECO:0000313|Proteomes:UP000245959};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:NMD86102.1, ECO:0000313|Proteomes:UP000576225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COR2-253-APC-1A {ECO:0000313|EMBL:NMD86102.1,
RC ECO:0000313|Proteomes:UP000576225};
RA Hitch T.C.A., Wylensek D., Clavel T.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVY36705.1}.
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DR EMBL; JABAEW010000008; NMD86102.1; -; Genomic_DNA.
DR EMBL; QEKH01000033; PVY36705.1; -; Genomic_DNA.
DR OrthoDB; 9783599at2; -.
DR Proteomes; UP000245959; Unassembled WGS sequence.
DR Proteomes; UP000576225; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:PVY36705.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245959};
KW Transferase {ECO:0000313|EMBL:PVY36705.1}.
FT DOMAIN 1..88
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 88..207
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 207 AA; 21777 MW; 46B5028E65161730 CRC64;
MTDFEALRAA VIKGKRNDVA AIVQAAIDGG EDINLILDRG MIPAMREIGD KFSRNEAYVP
ELLIAARAMQ AGLALLEPLI AASGRKSMGK VAIGTVKGDL HDIGKNLVAI MLKGAGYDVI
DLGVNCDITK YEEGVKQGAT IIGCSSLLTT TMPYMKEVVA YFKDKGVKVV IGGAPVTQAY
ADEIGADGYS EDANGAVKLI DSLLKTA
//
