ID   A0A2U1B7X3_9BACT        Unreviewed;       618 AA.
AC   A0A2U1B7X3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:NMD85653.1};
DE   SubName: Full=Peptidoglycan synthetase FtsI {ECO:0000313|EMBL:PVY44702.1};
GN   ORFNames=C8D82_10531 {ECO:0000313|EMBL:PVY44702.1}, HF882_03545
GN   {ECO:0000313|EMBL:NMD85653.1};
OS   Victivallis vadensis.
OC   Bacteria; Lentisphaerota; Lentisphaeria; Victivallales; Victivallaceae;
OC   Victivallis.
OX   NCBI_TaxID=172901 {ECO:0000313|EMBL:PVY44702.1, ECO:0000313|Proteomes:UP000245959};
RN   [1] {ECO:0000313|EMBL:PVY44702.1, ECO:0000313|Proteomes:UP000245959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14823 {ECO:0000313|EMBL:PVY44702.1,
RC   ECO:0000313|Proteomes:UP000245959};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:NMD85653.1, ECO:0000313|Proteomes:UP000576225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COR2-253-APC-1A {ECO:0000313|EMBL:NMD85653.1,
RC   ECO:0000313|Proteomes:UP000576225};
RA   Hitch T.C.A., Wylensek D., Clavel T.;
RL   Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVY44702.1}.
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DR   EMBL; JABAEW010000004; NMD85653.1; -; Genomic_DNA.
DR   EMBL; QEKH01000005; PVY44702.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1B7X3; -.
DR   OrthoDB; 9804124at2; -.
DR   Proteomes; UP000245959; Unassembled WGS sequence.
DR   Proteomes; UP000576225; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245959};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          57..231
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          277..595
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   618 AA;  69588 MW;  48720120EEA5935F CRC64;
     MLSTNDKIRR RIRILAAVIL IPIMLGLIAR FYYVQVIDHE FYLQEARKRY TTTRVTTGKR
     GEIFDVHGNL LVSNSPCVSI TCDPFNLTGD AQRRKLAFIL AKHLDDTYDS FYRKLNPVRQ
     RRGRDGKLLY RPDGSPDLVP NRYAMIDRNT SLQAAAKIKE QTKLNKIYAL VYKDSYMRTY
     PKGSLLSNVL GYTNVVDDVD VPQIGLERQM NAQMNPEEGR ERYERTRDGA PLSYGIHEFE
     QSRDGKNIYL TISEPIQAIL EEELDASYEK WQPATLYAAI ADPRTGNILA IAQRPTFNPN
     IRSTFTAEAA RTRIAEDSME PGSIIKPFTI GKALDWGFVT PQTEIDCNHG VWIYLNKPLR
     DSHPYDKLTV EGVIQKSSNI GTAKVAMMLG EQRVYQALKT FRFGDKTGLP FPIEESGLVL
     PVKKWDGLSI TRFPIGYGVR VTPLQMIRAY CALANNGKMP QLRLIDRLED PVTGEVTRIP
     SPPPVQMFDR PETCATLISM MIKVTQKGGT AVKAAIPGYE VAGKTGTSRK YIPTRRDSNG
     RIIERGHYAS GKYFSSFVGF VPARNPALVM LVTMDEPKGS YYAATVAAPT FKATMTRVLR
     HLNIQPDPAL LENNRTTP
//