ID   A0A2U1C2J0_9BURK        Unreviewed;       897 AA.
AC   A0A2U1C2J0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Acetyltransferase {ECO:0000313|EMBL:PVY55130.1};
GN   ORFNames=C8D04_0308 {ECO:0000313|EMBL:PVY55130.1};
OS   Simplicispira sp. 125.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Simplicispira.
OX   NCBI_TaxID=2135643 {ECO:0000313|EMBL:PVY55130.1, ECO:0000313|Proteomes:UP000245599};
RN   [1] {ECO:0000313|EMBL:PVY55130.1, ECO:0000313|Proteomes:UP000245599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=125 {ECO:0000313|EMBL:PVY55130.1,
RC   ECO:0000313|Proteomes:UP000245599};
RA   Chistoserdova L.;
RT   "Synthetic bacterial communities of pure cultures isolated from sediment of
RT   Lake Washington, USA.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVY55130.1}.
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DR   EMBL; QEKM01000001; PVY55130.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1C2J0; -.
DR   Proteomes; UP000245599; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245599};
KW   Transferase {ECO:0000313|EMBL:PVY55130.1}.
FT   DOMAIN          488..524
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   DOMAIN          733..897
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
SQ   SEQUENCE   897 AA;  96493 MW;  0ED30877C1BD1BF4 CRC64;
     MEKHYLTPLF SPETVAVFAG DCEDDAHLTS QAKALHEALR AQRYTGRLVF VDLQKTTGSL
     ADLVQTRADL AVIALPAADV AAALEVAGRM ACRAAMIVSS GIGPDLATQL KKIAHREGMY
     LLGPNSLGLQ RPALQLNASA AGPLARTGSL ALVSQSGALT ASILDWARNN AVGFSSVVSL
     GPNTDIDIAQ VLDFLANDPQ THSIVVYMEG ITSARAFMSA LRSAANAKPV VVLKAGRKPA
     GNEAAQTHSG TIVGSDDVFD AALRRAGAVR VRSFVALFSA AKCLASRYRP VGRRLAIVTN
     GGGPGVLAAD WVNEIFLDLG KLSPESAAAL KPQLPELASL SDLIDVSEDA TAEHYRIAVE
     AASKDRQIDG VLAIHSPKSG VDPSDVARVL AEVKRQMTKP LLTCWMGDAT VVPARGILLE
     ASIPSFRTPE AAVGAFGNIA AFHQNQQLLQ QTPPPLSALA KPDIKGARLV IESVLAERRK
     VLTEMESKTL LAAFHIPVTK TILARSAHEA MMIATQLGFP VALKIDSPDI SHKSDVQGVA
     LNVIDGASAR DTYTDMVARV ARLQPHARIN GVTVQNMVRA RRGREVCIGL VTDDPFGPVI
     TFGAGGTMIE LINDRAMELP PLNQFLARRL IERSRVAETL GEWRGATAAD HEALEQILLR
     VSEMVCQLPQ LREMDINPII VDESGAVAVD ARIVIDHAPH SGNGSVGQYG HLAILPYPAR
     YEQIWPLRGG GEYTVRPIRP DDAQMLQTLV QNLSPESRYF RFISSMAQLP PMMLARFTLI
     DYDREMALVA IFKERKAGPD GEIVETERIV GVSRYITNPD HSSCEFALVV ADDFSGKGLG
     SRLMLSIMDV ARDKGLAEIE GLVLANNPEM LKLMRNLGFS IKAYADDPEF KMVTHTL
//