ID   A0A2U1C4R2_9BURK        Unreviewed;       368 AA.
AC   A0A2U1C4R2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Saccharopine dehydrogenase-like NADP-dependent oxidoreductase {ECO:0000313|EMBL:PVY55874.1};
GN   ORFNames=C8D04_1090 {ECO:0000313|EMBL:PVY55874.1};
OS   Simplicispira sp. 125.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Simplicispira.
OX   NCBI_TaxID=2135643 {ECO:0000313|EMBL:PVY55874.1, ECO:0000313|Proteomes:UP000245599};
RN   [1] {ECO:0000313|EMBL:PVY55874.1, ECO:0000313|Proteomes:UP000245599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=125 {ECO:0000313|EMBL:PVY55874.1,
RC   ECO:0000313|Proteomes:UP000245599};
RA   Chistoserdova L.;
RT   "Synthetic bacterial communities of pure cultures isolated from sediment of
RT   Lake Washington, USA.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PVY55874.1}.
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DR   EMBL; QEKM01000001; PVY55874.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1C4R2; -.
DR   OrthoDB; 9769367at2; -.
DR   Proteomes; UP000245599; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11133:SF22; SACCHAROPINE DEHYDROGENASE [NADP(+), L-GLUTAMATE-FORMING]-RELATED; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245599}.
FT   DOMAIN          8..115
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          123..344
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   368 AA;  39180 MW;  C582BCDBF4664730 CRC64;
     MITTRRSITI LGAGHIGFAM ALLLSRSGDY DVLVADRDAA RLEAVAVLDV ATLATPDDAA
     LQTAVSGRYA VLNALPFHCA VGVATLCAQA GVHYFDLTED VQSTQAIRAL AQDARSVLMP
     QCGLAPGFIG IVGNDLACRF DELHSLRMRV GALPRYPQGA LRYNLTWSTE GLINEYCNPC
     EAIVDGQATT VAALDGLETF ALDGVEYEAF NTSGGLGTLT ETLAGRARQV DYKSIRYPGH
     CAILKLLLND LRLRDRRDLL KEIFEAAIPT TEQDVIVVFA SASGLRGGRL VQDSYSGRIL
     GTEVAGHRLS AIQRTTAAGI CTALDLVAQD KLPQKGFVGQ EAVALQDFLG NRFGQAYATE
     CAGEAVAA
//