ID A0A2U1C866_9BURK Unreviewed; 424 AA.
AC A0A2U1C866;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative N6-adenine-specific DNA methylase {ECO:0000313|EMBL:PVY57108.1};
GN ORFNames=C8D04_2381 {ECO:0000313|EMBL:PVY57108.1};
OS Simplicispira sp. 125.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Simplicispira.
OX NCBI_TaxID=2135643 {ECO:0000313|EMBL:PVY57108.1, ECO:0000313|Proteomes:UP000245599};
RN [1] {ECO:0000313|EMBL:PVY57108.1, ECO:0000313|Proteomes:UP000245599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=125 {ECO:0000313|EMBL:PVY57108.1,
RC ECO:0000313|Proteomes:UP000245599};
RA Chistoserdova L.;
RT "Synthetic bacterial communities of pure cultures isolated from sediment of
RT Lake Washington, USA.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVY57108.1}.
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DR EMBL; QEKM01000001; PVY57108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1C866; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000245599; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PVY57108.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245599};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000313|EMBL:PVY57108.1}.
FT DOMAIN 48..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 424 AA; 46518 MW; 5DF8387C75942848 CRC64;
MNQLQLFLPC AAGVEGFLAD EVHRITGLTG NDLLTGRGGV LLRASWRDAM LLNLHSRLAQ
RVLVQLAHRP YRNENDLYEA ASSVAWEIWF TTRQTFKVEV TAQHSPLTSL NFAGLRVKDA
VADRFRAKSG VRPDVNTQWP DIRIHLHLTT EEATVYIDTS GEPLFKRGWR EDKGDAPLKE
TLAAAMIAAS GWDPHGDAPM PLYDPCCGSG TVIIEAAQIA CRIAPGLRRR FAFEKLLPFQ
SHVWGAIKNA AHNEEQKSAV AIFGSDVSHR MVDFSQRNAE RAGVAGAIQL RGGDALQRMP
PCDAPGLMLL NPPYGERIAA AGAAGQNASE RAAQRAQGDA VGREAAHTDD GGEFFSQLAA
HWKKNYAGWT AWMLTPDLKL PSKMRLKESR RVPMWNGPIE CRLFRFDMVK GAVRAPRAGP
GDGG
//
