ID A0A2U1CH73_9BURK Unreviewed; 393 AA.
AC A0A2U1CH73;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:PVY60177.1};
GN ORFNames=C7440_3952 {ECO:0000313|EMBL:PVY60177.1};
OS Pusillimonas noertemannii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pusillimonas.
OX NCBI_TaxID=305977 {ECO:0000313|EMBL:PVY60177.1, ECO:0000313|Proteomes:UP000246145};
RN [1] {ECO:0000313|EMBL:PVY60177.1, ECO:0000313|Proteomes:UP000246145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10065 {ECO:0000313|EMBL:PVY60177.1,
RC ECO:0000313|Proteomes:UP000246145};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVY60177.1}.
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DR EMBL; QEKO01000013; PVY60177.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1CH73; -.
DR STRING; 1231391.GCA_000308195_01965; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000246145; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF138; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000246145};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:PVY60177.1}.
FT DOMAIN 5..263
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..391
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 349
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 379
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 393 AA; 40616 MW; 23FC8604E1716772 CRC64;
MSDPIVLVSI ARTPMGGMMG SLSGLAAHEL GAIAIKAAVE RAGISPDAVS EVIMGNVLQA
GQGQAPARQA ALGAGLPQAV GCTTIHKVCG SGLKAAMFAH DLLKAESADV IVAGGQESMS
NAPYLLLRGR QGYRYGHSTV YDHMALDGLE DAYQRGTAMG VFAESCAGKY SFSREQQDAF
ALESLRRARA ATEDGSFKWE IAPVTVAGRK GDTVIDTDEG PAKAMPEKIP TLKPAFKKDG
TVTAANASSI SDGAAAMVLM RESTAKKLGV APIARIVAQA QHSQEPEWFT TAPVGAMQKL
LEKAGWKTSD VDLYEINEAF AVVTMAAMND LKLDHAKVNI HGGATALGHP IGASGARLLA
TLVGALRTTG GKKGVASLCI GGGEAVAMAI EML
//
