ID A0A2U1CJK4_9BURK Unreviewed; 377 AA.
AC A0A2U1CJK4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=C7440_2731 {ECO:0000313|EMBL:PVY61181.1};
OS Pusillimonas noertemannii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pusillimonas.
OX NCBI_TaxID=305977 {ECO:0000313|EMBL:PVY61181.1, ECO:0000313|Proteomes:UP000246145};
RN [1] {ECO:0000313|EMBL:PVY61181.1, ECO:0000313|Proteomes:UP000246145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10065 {ECO:0000313|EMBL:PVY61181.1,
RC ECO:0000313|Proteomes:UP000246145};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVY61181.1}.
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DR EMBL; QEKO01000004; PVY61181.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1CJK4; -.
DR STRING; 1231391.GCA_000308195_01086; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000246145; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000246145}.
FT DOMAIN 19..360
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 377 AA; 41144 MW; CC340B73428BC024 CRC64;
MSTDLLFDTL EAGNGRRIAV ATLNRPRTLN GLTLQMCADL DRQLTLWEED DAVALVVLRG
EGGKAFCAGG DLHSLYASMR EATPGDAWGN EYARDFFAVE YRLDYHIHRY AKPVLCWGSG
IVMGGGVGLM MGASHRVVTE TTRFAMPEIT IGIFPDVGAS WMLERLPAGI GTFLALTGAQ
LDAADCRHLG LADYTLHSGG WQALVRALQG TPWSSGRNEN AVLLDRVLRS LAPTDMNCPA
PLRKLYERIA EQCDGPDFEA ICAGIAGWHD ASNTWLARAA QTFMRGSPGS ARLGFTLQKK
ARGLSLAQVF QMEYTAILQC VAGENFREGV RALLIDKDMS PRWQPSSIAQ ADEEWVQRFF
VPAWPAGVAH PLADLGV
//
