ID A0A2U1EDM9_9PSEU Unreviewed; 659 AA.
AC A0A2U1EDM9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:PVY97972.1};
GN ORFNames=C8D89_12227 {ECO:0000313|EMBL:PVY97972.1};
OS Actinomycetospora cinnamomea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinomycetospora.
OX NCBI_TaxID=663609 {ECO:0000313|EMBL:PVY97972.1, ECO:0000313|Proteomes:UP000245639};
RN [1] {ECO:0000313|EMBL:PVY97972.1, ECO:0000313|Proteomes:UP000245639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45771 {ECO:0000313|EMBL:PVY97972.1,
RC ECO:0000313|Proteomes:UP000245639};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVY97972.1}.
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DR EMBL; QEKW01000022; PVY97972.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1EDM9; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000245639; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245639}.
FT DOMAIN 37..89
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 99..472
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 539..613
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 659 AA; 71979 MW; 6462245F7EB511CA CRC64;
MTETLWTPTA KRIHDSPLRA YLDWLEEREG RAFPDHDTLW AWSVEDVDRF WVSVVDYFEV
AFSSPWTQVR TADPMPHTRW FTGARLNWAQ HLLRHGDDDA PALVCVQEGA RPEREITWGE
LRRSVAAAAG WLRRAGVRPG DRVGAYLPNT EHAVIACLAT AAVGAVWACC SPDFGAEGTI
GRLAQLEPTV LIAVDGYHWN GKEIDRADVV ARLREDLPTV QHVVGVPYVF DRPQPAGTTS
WDDLLAGVEG GGDEPLEFEQ VEFSHPLWVL FTSGTTGLPK GLVHGHGGIT LQGLMWSGLY
AGLRRGERMF TYTSTGWALW NIELGALTQG ASIVLYEGAP NHPPGAVWEV AARTGADVVL
MGAAVVTATA GTGVSPRREH DLSRLRTVMF SGSALPPDGY HWVMEHVSPD VRIDSTSGGT
DISGSFVGAN EYAPVRVGRI GGPIAGVDCA AWDEAGHPVV DEVGDLVITQ PMPSMPVYLW
NDPEAVRYTE SYFDTWPGVW RHGDWVTMHS DGGVSIHGRS DSTLNRGGVR LGSSDFYDVL
ETMPEIVETL VVGVDLPDGG YWLGLFVVPA PGHELDDALK EKIVTTLRSR LTPRHTPDEI
LEAPAVPHTL TGKRLEVPIK KLLSGRPLEK AANIASVDDP DALRWYARFA ADRRSSTAG
//
