ID A0A2U1FQX9_9PSEU Unreviewed; 461 AA.
AC A0A2U1FQX9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=GntR family transcriptional regulator/MocR family aminotransferase {ECO:0000313|EMBL:PVZ14556.1};
GN ORFNames=C8D89_101421 {ECO:0000313|EMBL:PVZ14556.1};
OS Actinomycetospora cinnamomea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinomycetospora.
OX NCBI_TaxID=663609 {ECO:0000313|EMBL:PVZ14556.1, ECO:0000313|Proteomes:UP000245639};
RN [1] {ECO:0000313|EMBL:PVZ14556.1, ECO:0000313|Proteomes:UP000245639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45771 {ECO:0000313|EMBL:PVZ14556.1,
RC ECO:0000313|Proteomes:UP000245639};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVZ14556.1}.
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DR EMBL; QEKW01000001; PVZ14556.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1FQX9; -.
DR OrthoDB; 5415143at2; -.
DR Proteomes; UP000245639; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:PVZ14556.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000245639};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:PVZ14556.1}.
FT DOMAIN 18..86
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 461 AA; 48453 MW; 8AE8EC2D6B850D5C CRC64;
MRGLPPELVL PLDRSVPTPL AVQLADGLRD AAARGVLRVG HRVPSTRSLA EELGVSRTVT
AAAYDQLVAE GWLGPRRGAG TYVLATSHVR DLLSYSSEDH ARGEALIDLR PGAPCTEVLD
RRAWRRAWRR AGDLELATRP EHAGVPAYRD AVARLLLHHR GLAAAPDDVL ATSGTTDGCA
EVIALLAADR GRPPRVAVED PGYLRATALL RDAGAEVVGV GVDDEGLRVD DVPGGVDAVY
VTPAHQYPLG ARLPVARRAA LVARARDEGL LLVEDDYDGE LRYDVAPLPL LAGLGPDVTV
HLGTTSKVLT PTLGAGWMVA PPAWRERVLA RRRATGVRPP PAGQQVVAAL HADGALARHL
ARLRRELAAR RARVVDAVAA GGHAVRGDRA GAHLVVPLPD GAAEDAVVDE AAHHGVHLTA
LGPCHLDPAV PRACGVLVGW AGPTAAELDD ALRRLTTVLG G
//
