ID A0A2U1KG66_ARTAN Unreviewed; 478 AA.
AC A0A2U1KG66;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=NAD(P)-binding Rossmann-fold superfamily protein {ECO:0000313|EMBL:PWA35701.1};
GN ORFNames=CTI12_AA607060 {ECO:0000313|EMBL:PWA35701.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA35701.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA35701.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA35701.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA35701.1}.
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DR EMBL; PKPP01019551; PWA35701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1KG66; -.
DR STRING; 35608.A0A2U1KG66; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43180; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210); 1.
DR PANTHER; PTHR43180:SF41; SHORT-CHAIN DEHYDROGENASE REDUCTASE 2A; 1.
DR Pfam; PF00106; adh_short; 2.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
SQ SEQUENCE 478 AA; 50179 MW; 445A1E53D37FE1FD CRC64;
MHANGKEITN SILSRRLEGK VAIVTGGAGG IGAATVRLFV KHGANVVIAD INDEFGLGLA
SLLSPLATYV HCDVSMENDV QNLFDSTISS YGRVDILFNN AGVLGNQSKH KSIVNFDVDE
FDRVMSVNVR GVALGMKHAA RVMIPRGSGC IISTASVASV MGGMGPHAYT ASKHAIVGLT
KNAACELGRY GVRVNCISPF GVATSMLVAI VTGGAGGIGA ATVRLFVKHG ANVVIADIND
EFGLGLASLL SPLATYVHCD VSMENDVQNL FDSTISSYGR VDILFNNAGV LGNQSKHKSI
VNFDVDEFDR VMSVNVRGVA LGMKHAARVM IPRGSGCIIS TASVASVMGG MGPHAYTASK
HAIVGLTKNA ACELGRYGVR VNCISPFGVA TSMLVNAWRD EDVDDENGEI SFRPPNDKEI
EKTENFVNSL GILKGATLKA KDIAEAALYL ASDESKYVSG HNLVVDGAVT TSKNCVNL
//
