ID A0A2U1KGW5_ARTAN Unreviewed; 523 AA.
AC A0A2U1KGW5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Toll/interleukin-1 receptor (TIR) domain-containing protein {ECO:0000313|EMBL:PWA36006.1};
GN ORFNames=CTI12_AA604260 {ECO:0000313|EMBL:PWA36006.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA36006.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA36006.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA36006.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA36006.1}.
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DR EMBL; PKPP01018967; PWA36006.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1KGW5; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF340; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Receptor {ECO:0000313|EMBL:PWA36006.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 11..177
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 523 AA; 59047 MW; 653496FC040B1CD2 CRC64;
MASSSSSSRS FKYDVFLSFR GEDTRKSFVD HLHTALQQRL IRTYKDDITL PRGESVGPAL
LKAIDESTIA VVIFSKNFAV SSWCLDELLY IMKCREEMEL TVIPVFYDVD PSDVRKQIGE
FGKAFAKQET ENVTKAELWR RALVAASNIS GWEPKNVSNG YEAAVIQNII DVISDKLLSS
NSDIDEELVG MTDRVKDLIS RLEIGTGGLR IVGIWGVGGG GKTTLATSVY MKINDHFQGH
CIVDNIREES SKHGRTTLQA KILSTLLKTE VRVQSEEEGK CLIKSRLCHS NVLILLDDVD
DCKQLEALAG SHQWFGDGSR IIITTRDEHV LRTQKVDHIS PVTLLSQDEG IRLFKKHAYN
EEEPLKNYGI LALRVVSYAH GLPLALKVLG SFLYDKDEKE WMSTLDRLKD IPDTDIVKQL
KISYDGLKKV EKELFLDIAC FFRGHPKDNA MEIFEACGFH PDIGIKVLIQ KALITIDRRG
KFDMHDLVQE MGHYIVRGEH PDNPKCKISA RSDLQDRIMN DIM
//
