ID A0A2U1KIS4_ARTAN Unreviewed; 281 AA.
AC A0A2U1KIS4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=ENTH/VHS/GAT family protein {ECO:0000313|EMBL:PWA36632.1};
GN ORFNames=CTI12_AA597950 {ECO:0000313|EMBL:PWA36632.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA36632.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA36632.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA36632.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA36632.1}.
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DR EMBL; PKPP01017877; PWA36632.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1KIS4; -.
DR STRING; 35608.A0A2U1KIS4; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 2.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898:SF2; TARGET OF MYB PROTEIN 1; 1.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 2.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 2.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 25..86
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 105..139
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 199..281
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
SQ SEQUENCE 281 AA; 30782 MW; 9F885B9C39C71C45 CRC64;
MLPATGFSSS SSASANSVVV RVDKATSEFL NGPDWTLNID ICDTLNANPW LAKDVVKALK
KRLQHKNPNV QLLSLTIIKN MLPATGFSSS SSASANSVVV RVDKATSEFL NGPDWTLNID
ICDTLNANPC RAHCSTAART QPQPRLHKPH QYGIQFPERS PDAAPIFTPP VTHPSLRSPQ
ANYGMPINSS TRLDEAMASE IENLSESMIE SMRNVSDLLS EMLQEIDPND RAAVKDEVIV
DVVDRCRSNQ KKLMEMLAST IFRSIYHQKS VGIASLMKSS S
//
