ID A0A2U1KK51_ARTAN Unreviewed; 1278 AA.
AC A0A2U1KK51;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=NB-ARC domains-containing protein {ECO:0000313|EMBL:PWA37108.1};
GN ORFNames=CTI12_AA594530 {ECO:0000313|EMBL:PWA37108.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA37108.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA37108.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA37108.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA37108.1}.
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DR EMBL; PKPP01017225; PWA37108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1KK51; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1237; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1278
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015705555"
FT DOMAIN 12..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 188..391
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1278 AA; 144872 MW; 33E02C994545BC81 CRC64;
MAELILSALL PIVFEKLASA AVKKIARAKE IDSELKKWRE SLSMIQDVLN DAAEKEVTEA
AVKRWLNRLH HLAYDIDDIL DDMATEAMHR EFTNESEATT SKLRKLIPTC CTCFSLSTTS
MDGKLSDITT RLQELVDEKN NLGLIVRDGR TKNKNRNQET SSKRETIVGR DGDKEILLPK
LLGGEPCSQN FSIVAIVGMG GMGKTTLARL LYNDKLVKDH FDHKAWVCVS EDFDSFKISK
EIFQSVSGET QKFESLDLLQ KALEDRLMGK RFLIVLDDVW SDKLEDWETL AGPFYKGAPG
SKIIITTRKT ELLRRLHHVH QYDLQKLSHD DALCLFAQHA GLDDFDSYEA QRKHAEGIVQ
KCAGLPLAIK ALGSLLRTKA DEEEWKDVLN NDLWKLKDGG VIVPALRLSY QDLSARLKQL
FAYCSLLPKD YVFKKEDLIL KWMAEGFLHQ SDTNTSMERL GDKCFQELLS KSFFQHVPGD
DKSLFMMHDL MNDLATLVAG EFIIRLDIGM EKDDGEEVLK RYRHMSFVPE RYTTYNKLKS
FRKANSLRTF LAVPIVVGES WHVFNISSKI LVDLLPKLPL LRVLCLSKLE IDEVPESVGN
MKHLRYLNLS QNRITHLPDN VCNLINLQTL IVSGCEMLTK LPDNLKKLKS LRHFDIRDTF
LWNMLPEGMD KLKGLQILSN IIVGENDNFP ISGLRNLKNL QGKIYIRGLE QVKSARDIRE
VKLSQKRVSG LELEWRDVFD DSRNETLENE VLSALMPHSE NLEDLSIKSY GDKVFPNWLG
DSKFVRLSCI SLSRCRNCTR LPPLGNLPSL KKLFIKDLDE VKDVGSEFVG AGSGPAFPSL
ESLRFEDMRG WKVWSTTVGG GVGAVFPCLQ ELTLRNCPNL AVVSLKPLPS LRVLKISDCG
DGVLRSLIRV ASSVTMLSIE GISGLTDEVW RDTMEQLGAV EELSIRKCNE IKYMWESEAE
ASKVLVNIRK LEVWNCEELV SLGEKEEEND NSGCNHLTSL KNMVLWSCKN LERFSCPDNI
ESLFIWGCGS ITCVSFPTGG CQKLKSLTIK FCNQLSEKEL EKVFPITITS MLEVVYVSYW
PNLKSVNELT NKFIRLTQLF ISDCSRIESF PADVLPTFTS LKRLSIFNCK NMDVASFGLW
PPNLGFLQIG ALKKPISQWS PQTFPTSLVH LILDGGSGEE DDVTGGSQLS HMLPSSLTNL
KLWEFEKLET VSKGLQHLTS LQHLQIRGCP KMKDLPEELL PSLLSLWLIK CPDELKEKIS
RRGSYWPRIS YIPHVRIE
//
