ID A0A2U1KZZ5_ARTAN Unreviewed; 588 AA.
AC A0A2U1KZZ5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Signal recognition particle receptor alpha subunit family protein {ECO:0000313|EMBL:PWA42335.1};
GN ORFNames=CTI12_AA547280 {ECO:0000313|EMBL:PWA42335.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA42335.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA42335.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA42335.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC {ECO:0000256|ARBA:ARBA00008531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA42335.1}.
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DR EMBL; PKPP01012472; PWA42335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1KZZ5; -.
DR STRING; 35608.A0A2U1KZZ5; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005785; C:signal recognition particle receptor complex; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005047; F:signal recognition particle binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR CDD; cd14826; SR_alpha_SRX; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.20.120.140; Signal recognition particle SRP54, nucleotide-binding domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007222; Sig_recog_particle_rcpt_asu_N.
DR InterPro; IPR013822; Signal_recog_particl_SRP54_hlx.
DR InterPro; IPR036225; SRP/SRP_N.
DR InterPro; IPR000897; SRP54_GTPase_dom.
DR InterPro; IPR042101; SRP54_N_sf.
DR PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR PANTHER; PTHR43134:SF1; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF04086; SRP-alpha_N; 1.
DR Pfam; PF00448; SRP54; 2.
DR Pfam; PF02881; SRP54_N; 1.
DR SMART; SM00962; SRP54; 1.
DR SUPFAM; SSF47364; Domain of the SRP/SRP receptor G-proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00300; SRP54; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:PWA42335.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 561..574
FT /note="SRP54-type proteins GTP-binding"
FT /evidence="ECO:0000259|PROSITE:PS00300"
FT REGION 125..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 65290 MW; 1F4B8AB9296B3B8B CRC64;
MLEQLLIFTR GGLILWATCK ELGNALRGSP IDTFIRACLL EERSGAASYN YDVPGASYTL
KWTFHNELGI VFVAVYKKIF HLLYVDDLLA MVKREFSEIY DPKRMVYDDF DETFRQLRKE
AEARAEEMKK SKQVMAKPVS NMGKKQGQQM QKMGFEGGNK KQSDDGESGK DGENGDDVKT
GCVQNDHSNG EIANKGRVNG KENGNNNSNG GAFDLNKLQK LRSKGGKKAN VVNKVSKEEP
KKKPVKKNRV WDDKPVETKL ETKLDYTDPA GEIGDNGRMA IPQVVEGESM MDKDEYVSSD
SESEEDDEAD ADKKVDSKKK GWFTSMFQSI AGKANLEKAD LEPALNALKD RLMTKNVAEE
IAEKLCESVA FSLEGKMLAS FTRISSMVQT AMEDALFRIL TPKRSIDILR DVHVAKEQRK
PYVVVFVGVN GVGKSTNLAK VAYWLQQHDI NVMIAACDTF RSGAIDQLLT HACTLQIPYI
EKDQSVCCEH SWSNADLVLF VGEALVGNDA VDQLSKFNQK LADLSPSPSP RLIDGILLTK
FDTIDEKVGA ALSMVYISGA PVMFLGCGQS YTDLKKLNVK SIVKTLLK
//
