ID A0A2U1L8F4_ARTAN Unreviewed; 633 AA.
AC A0A2U1L8F4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolases superfamily protein {ECO:0000313|EMBL:PWA45269.1};
GN ORFNames=CTI12_AA519090 {ECO:0000313|EMBL:PWA45269.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA45269.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA45269.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA45269.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-14 subfamily.
CC {ECO:0000256|ARBA:ARBA00010899}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA45269.1}.
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DR EMBL; PKPP01010853; PWA45269.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1L8F4; -.
DR STRING; 35608.A0A2U1L8F4; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR PANTHER; PTHR47972:SF52; P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00033; CH; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:PWA45269.1};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 1..106
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 313..473
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 161..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 480..507
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 171..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 70870 MW; 8D03BA0E30AA7FCF CRC64;
MRTAVIEWLN STLPNLNLPV NASDEEFRIL LVDGTILCQL MNQLGPGPAI EYGNPHHSSE
TPSENVNKFL AAMDEMSLPH FNISDLEKRV ACLMRKVVQE IERRISTQAE HLRTQNNLFK
TREEKYQSRI RVLEALENGT SGESTEVINH FDHMKVDVTR TGNSKDSALQ TDKTTLHEEK
RTENQEVERK MNEKDNNSAE IAALKQELEN VRKSHKDHCL QLENAAKKAQ NDLEKTLHEV
ENHLDESNRK VKQLEDKSRS KSQWWNKKEH IYKTFTEFQL GALKELRFAS QSVRQELLKT
QKSYTEDIGH LAVPDANMRQ VNETSDVLGL MEIGFRNRAR STTSMNERSS RSHSVVTIHV
RGTDLKNGGS LNAGLHLVDL AGSERVDRSE VVGDRLKEAQ NINKSLAALG DVIYSLSQKN
AHVPFRNSKL TQVLQSSLGG QAKTLMFVQL NPEAASYSES LGTLKFADRV SGVELGPAQN
NKASSNVKEL MEQVASLKHT ITKKDAEIER LQVSKDKRNG HPPIGMEKQR SVRYGSSSPV
SKGLNNRSES MRVGRMSLDG YTYGYRPKKG PSSLHGEDTD NSSVASSVES SPSHEGSKSL
HNTNKPKSGN RISRPLQKIS KDLPKAAKGN NNT
//
